Abstract
It is well established that aza analogs of purines, pyrimidines and their nucleosides possess significant but varying potency as antineoplastic agents [1–7]. Thus, for example, 6-azacytidine is an inhibitor for orotidylic acid decarboxylase [3] and 6-azauracil inhibits the development of animal tumors [4] and human acute leukemia [5]; similarly, 8-azaguanine is a highly effective anti-neoplastic agent [6] and also inhibits animal tumors [7].
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© 1976 D. Reidel Publishing Company, Dordrecht-Holland
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Hodgson, D.J., Singh, P. (1976). Intra- and Intermolecular Interactions in Azanucleosides. In: Pullman, B. (eds) Environmental Effects on Molecular Structure and Properties. The Jerusalem Symposia on Quantum Chemistry and Biochemistry, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-1837-1_20
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DOI: https://doi.org/10.1007/978-94-010-1837-1_20
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