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The Watson-Crick Model and Reductionism

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Topics in the Philosophy of Biology

Part of the book series: Boston Studies in the Philosophy of Science ((BSPS,volume 27))

Abstract

There are a number of interrelated problems that cluster around the issue of reduction in the sciences. The logical analysis of theory, the meaning of theoretical terms, the nature of scientific explanation, and various theses concerning the nature of scientific progress, are all closely connected with the problem of intertheoretic reduction. The recent influential and important works of T. S. Kuhn (1962) and P. Feyerabend (1962) are a testimony to the centrality of the analysis of reduction in philosophy of science.

An earlier version of this paper was read to the 155th National Meeting of the American Chemical Society, San Francisco, April 1968.

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References

  • Avery, O. T., MacLeod, C. M., and McCarty, M.: 1944, ‘Studies on the Chemical Nature of the Substance Inducing Transformation of Pneumococcal Types’, J. Exp. Med. 79, 137.

    Article  Google Scholar 

  • Benzer, S.: 1957, The Elementary Units of Heredity’, The Chemical Basis of Heredity (eds. W. D. McElroy and B. Glass), Baltimore: Johns Hopkins.

    Google Scholar 

  • Benzer, S.: 1962, The Fine Structure of the Gene’, Scientific American 206, 70.

    Google Scholar 

  • Bonner, J.: 1965, The Molecular Biology of Development, Oxford: Clarendon Press.

    Google Scholar 

  • Born, M. and Wolf, E.: 1959, Principles of Optics, New York: Pergamon.

    Google Scholar 

  • Cairns, J.: 1963, ‘An Estimate of the Length of the DNA Molecule of T2 Bacteriophage by Autoradiography’, J. Mol. Biol. 6, 208.

    Article  Google Scholar 

  • Cairns, J., Stent, G. S., and Watson, J. D. (eds.): 1966, Phage and the Origins of Molecular Biology, Cold Spring Harbor, New York: Cold Spring Harbor Laboratory of Quantitative Biology.

    Google Scholar 

  • Carlson, E. A.: 1966, The Gene: A Critical History, Philadelphia: W. B. Saunders.

    Google Scholar 

  • Chargaff, E.: 1950, ‘Chemical Specificity of Nucleic Acids and Mechanism of Their Enzymatic Degradation’, Experentia 6, 201.

    Article  Google Scholar 

  • Crick, F. H. C.: 1957, The Structure of Nucleic Acids and Their Role in Protein Synthesis’, Biochem. Soc. Symp. 14, 25.

    Google Scholar 

  • Crick, F. H. C.: 1958, ‘On Protein Synthesis’, Symp. Soc. Exp. Biol. 12, 138.

    Google Scholar 

  • Duhem, P.: 1962, The Aim and Structure of Physical Theory. Trans. by P. P. Wiener from 1914 edition. New York: Atheneum.

    Google Scholar 

  • Einstein, A.: 1931, ‘Maxwell’s Influence on the Development of the Conception of Physical Reality’, James Clerk Maxwell: A Commemoration Volume 1831–1931. Cambridge: Cambridge University Press.

    Google Scholar 

  • Feyerabend, P. K.: 1962, ‘Explanation, Reduction, and Empiricism’, Minnesota Studies in the Philosophy of Science. Vol. 3 (eds. H.Feigl and G.Maxwell), Minneapolis:University of Minnesota Pre

    Google Scholar 

  • Feyerabend, P. K.: 1965, ‘Reply to Criticism’, Boston Studies in the Philosophy of Science. Vol. 2 (eds. R. S.Cohen and M. W. Wartofsky), New York: Humanities Pre

    Google Scholar 

  • Fine, A.: 1967, ‘Consistency, derivability, and Scientific Change’, J. Phil. 64, 231.

    Article  Google Scholar 

  • Goodman, N.: 1966, The Structure of Appearance, 2nd edn. Indianapolis: Bobbs-Merrill.

    Google Scholar 

  • Hershey, A.D. and Chase, M.: 1952, ‘Independent Functions of Vital Protein and Nucleic Acid in Growth of Bacteriophage’, J. Gen. Physiol. 36, 39.

    Article  Google Scholar 

  • Hertz, H.: 1890, ‘On the Fundamental Equations of Electromagnetics for Bodies at Rest’ Trans. by D. E. Jones from Göttinger Nachr. (1890) in Electric Waves (1893/1962). New York: Dover.

    Google Scholar 

  • Hesse, M. B.: 1968a, Tine’s Criteria for Meaning Change’, J. Phil., 65, 46.

    Article  Google Scholar 

  • Hesse, M. B.: 1968b, ‘Review of I. Scheffler’s’, Science and Subjectivity, B.J.P.S. 19, 176.

    Google Scholar 

  • Hoagland, M. B., Zamecnik, P. C., and Stephenson, M. L.: 1957, ‘Intermediate Reactions in Protein Biosynthesis’, Biochem. Biophys. Acta 24, 215.

    Article  Google Scholar 

  • Ingram, V. M.: 1956, ‘A Specific Chemical Difference Between the Globins of Normal Human and Sickle-Cell Anaemia Haemoglobin’, Nature 178, 792.

    Article  Google Scholar 

  • Jacob, F. and Monod, J.: 1961, ‘Genetic Regulatory Mechanisms in the synthesis of Proteins’, J. Mol. Biol. 3, 318.

    Article  Google Scholar 

  • Jukes, T.: 1966, Molecules and Evolution, New York: Columbia University Press.

    Google Scholar 

  • Kaiser, A. D.: 1962, ‘The Production of Phage Chromosome Fragments and Their Capacity for Genitic Transfer’, J. Mol. Biol. 4, 275.

    Article  Google Scholar 

  • Kornberg, A.: 1960, ‘Biologic Synthesis of Deoxyribonucleic Acid’, Science 131,1503.

    Article  Google Scholar 

  • Kuhn, T. S.: 1962, The Structure of Scientific Revolutions, Chicago: University of Chicago Press.

    Google Scholar 

  • Maxwell, J. C.: 1861, ‘On Physical Lines of Force’, Phil Mag. 21,161, 281, 338. Also continued in (1862) Phil Mag. 23, 12, 85.

    Google Scholar 

  • Maxwell, J. C.: 1865, ‘A Dynamical Theory of the Electromagnetic Field’, Royal Soc. Phil. Trans. 65, 459.

    Article  Google Scholar 

  • Maxwell, J. C.: 1968, ‘On a Method of Making a Direct Comparison of Electrostatic with Electromagnetic Force; with a Note on the Electromagnetic Theory of Light’, Royal Soc. Phil Trans. 158, 643.

    Article  Google Scholar 

  • Meselson, M. and Stahl, F. W.: 1958, ‘The Replication of DNA in Escherida coli.’ Proc. Natl. Acad. Sci. U.S. 44, 678.

    Article  Google Scholar 

  • Nagel, E.: 1961, The Structure of Science, New York: Harcourt, Brace, and World.

    Google Scholar 

  • Nirenberg, M. and Matthaei, J. H.: ‘The Dependence of Cell-Free Protein Synthesis in E. coli upon Naturally Occurring or Synthetic Polyribonucleotides’, Proc. Natl. Acad. Sci. U.S. 47, 1588.

    Google Scholar 

  • Oparin, A. I.: 1962, Life: Its Nature, Origin, and Development, Trans. by A. Synge. New York: Academic Press.

    Google Scholar 

  • Pauling, L., Itano, H. A., Singer, G. J., and Wells, I. C.: 1949, ‘Sickle Cell Anemia, a Molecular Disease’, Science 110, 543.

    Article  Google Scholar 

  • Perutz, M. F.: 1962, Proteins and Nucleic Acids: Structure and Function, Amsterdam: Elsevier.

    Google Scholar 

  • Polanyi, M.: 1967, ‘Life Transcending Physics and Chemistry’, Chem. Eng. News 45, 54.

    Article  Google Scholar 

  • Polanyi, M.: 1968, ‘Life’s Irreducible Structure’, Science 160, 1308.

    Article  Google Scholar 

  • Putnam, H.: 1962, ‘The Analytic and the Synthetic’, Mimesola Studies in the Philosophy of Science. Vol. 3 (Eds. H. Feigel and G. Maxwell), Minneapolis: University of Minnesota Press.

    Google Scholar 

  • Quine, W. V.: 1961, ‘Two Dogmas of Empiricism’, From a Logical Point of View, 2nd edn., Cambridge: Harvard University Press.

    Google Scholar 

  • Ravin, A. W.: 1965, The Evolution of Genetics, New York: Academic Press.

    Google Scholar 

  • Schaffner, K. F.: 1967a, ‘Approaches to Reduction’, Phil Sci. 34, 137.

    Article  Google Scholar 

  • Schaffner, K. F.: 1967b, ‘Antireductionism and Molecular Biology’, Science 157, 644.

    Article  Google Scholar 

  • Schaffner, K. F.: 1967c, ‘The Logic and Methodology of Reduction in the Physical and Biological Sciences’, unpublished Ph.D. dissertation, olumbia University.

    Google Scholar 

  • Schaffner, K. F.: 1969, ‘Theories and Explanations in Biology’, J. Hist. Biol. 2, 19.

    Article  Google Scholar 

  • Scheffler, I.: 1967, Science and Subjectivity, Indianapolis: Bobbs-Merrill.

    Google Scholar 

  • Sellars, W.: 1963, Theoretical Explanation’, Philosophy of Science: The Delaware Seminar (Ed. B. Baumrin), New York: Interscience.

    Google Scholar 

  • Stent, G. S.: 1968, ‘That Was the Molecular Biology that Was’, Science 160, 380.

    Google Scholar 

  • Taylor, J. H., Woods, P. S., and Hughs, W. L.: 1957, The Organization and Duplication of Chromosomes as Revealed by Autoradiographic Studies Using Tritium-Labeled Thymine’, Proc. Natl. Acad. Sci. U.S. 43, 122.

    Article  Google Scholar 

  • Taylor, J. H.: 1965, Selected Papers on Molecular Genetics, New York: Academic Press.

    Google Scholar 

  • Watson, J. D.: 1968, The Double Helix, New York: Atheneum.

    Google Scholar 

  • Watson, J. D. and Crick, F. H. C.: 1953a, ‘Molecular Structure of Nucleic Acids: a Structure for Deoxyribose Nucleic Acid’, Nature 171, 737.

    Article  Google Scholar 

  • Watson, J. D. and Crick, F. H. C.: 1953b, ‘Genetical Implications of the Structure of Deoxyribose Nucleic Acid’, Nature 171, 964.

    Article  Google Scholar 

  • Whitehouse, H. L. K.: 1965, Towards an Understanding of the Mechanism of Heredity, New York: St. Martin’s Press.

    Google Scholar 

  • Whittaker, E. T.: 1960, A History of the Theories of Aether and Electricity, Vol. I, New York: Harper and Brothers.

    Google Scholar 

  • Wilkins, M. H. F.: 1956, ‘Physical Studies of the Molecular Structure of Deoxyribose Nucleic Acid and Nucleoprotein’, Cold Spring Harbor Symp. Quant. Biol. 21, 75.

    Google Scholar 

  • Yanofsky, C., Carlton, B. C., Guest, J. R., Helsinki, D. R., and Henning, U.: 1964, ‘On the Colinearity of Gene Structure and Protein Structure’, Proc. Natl. Acad. Sci. U.S. 51, 266.

    Article  Google Scholar 

  • Zubay, G. L.: 1968, Papers in Biochemical Genetics, New York: Holt, Rinehart, and Winston.

    Google Scholar 

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Authors and Affiliations

  1. University of Pittsburgh, USA

    Kenneth F. Schaffner

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  1. Kenneth F. Schaffner
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© 1976 D. Reidel Publishing Company, Dordrecht, Holland

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Schaffner, K.F. (1976). The Watson-Crick Model and Reductionism. In: Topics in the Philosophy of Biology. Boston Studies in the Philosophy of Science, vol 27. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-1829-6_4

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  • DOI: https://doi.org/10.1007/978-94-010-1829-6_4

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-277-0596-9

  • Online ISBN: 978-94-010-1829-6

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