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Recent Studies on the Effects of Divalent Metal Ions on the Structure and Function of Nucleic Acids

  • G. L. Eichhorn
  • J. Rifkind
  • Y. A. Shin
  • J. Pitha
  • J. Butzow
  • P. Clark
  • J. Froehlich
Part of the The Jerusalem Symposia on Quantum Chemistry and Biochemistry book series (JSQC, volume 9-1)

Abstract

Metal ions are required for many of the processes in which nucleic acids transfer genetic information (Eichhorn, 1973). Thus metal ions are essential for the proper functioning of the genetic apparatus. Nevertheless the presence of the wrong metal ions, or even the essential ones in the wrong concentration, can lead to errors. Let me illustrate such errors in DNA, RNA and protein synthesis.

Keywords

Metal Binding Negative Ellipticity Intramolecular Crosslinks Genetic Information Transfer Bovine Pancreatic DNAse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© D. Reidel Publishing Company 1977

Authors and Affiliations

  • G. L. Eichhorn
    • 1
  • J. Rifkind
    • 1
  • Y. A. Shin
    • 1
  • J. Pitha
    • 1
  • J. Butzow
    • 1
  • P. Clark
    • 1
  • J. Froehlich
    • 1
  1. 1.Gerontology Research CenterNational Institute on Aging, National Institutes of Healthy, Baltimore City HospitalsBaltimoreUSA

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