Advertisement

Report on a preparation of snake venom (from Bothrops jararaca): Botropase®

  • M. Verstraete

Abstract

Botropase® is a coagulant fraction having a thrombin-like activity which is extracted from the venom of Bothrops jararaca.

Keywords

Disseminate Intravascular Coagulation Disseminate Intravascular Coagulation Snake Venom Fibrin Monomer Haemostatic Agent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Blombäck B., Blombäck M. and Nillson L.M. (1957) Coagulation studies on Reptilase, an extract of the venom of Bothrops atrox. Thrombos. Diathes. haemorrh. (Stuttg.) 1, 76.Google Scholar
  2. Cazzola D. (1957) Sull’impiego del veleno di Bothrops Jararaca come coagulante in ostetrica e ginecologia. Ginec. Obstet. Méx. 7, 12.Google Scholar
  3. Delaruelle J. and Marquet J. (1976) Coagulant fractions of snake venom and the control of capillary bleeding during microsurgery of the ear. In vivo demonstration. Arch. Otolaryng. In press.Google Scholar
  4. DE Nicola P., Guccione G., Manara G. and Cipolli P.L. (1969) Manifestazioni emorragiche in pazienti con reperti normali dell emocoagulazione e dell’emostasi. Minerva otorinolaring. 17, 183.Google Scholar
  5. Dinelli C.A., Montani E. and Sala E. (1959) Ricerche sperimentali in vitro sull’azione dell’emocoagulase del veleno di Bothrops Jararaca. Haematologica 355.Google Scholar
  6. Durante L.J., Moutsos A., Ambrose R.B., Duncan W.J., Fleming W., Zinsser H.H. and Phillips L.L. (1962) Prostatectomy bleeding. Ann. Surg. 156, 781.PubMedCrossRefGoogle Scholar
  7. Gibelli A. and Giarola P. (1973) Sulla standardizzazione delle frazioni coagulanti del veleno di Bothrops nella terapia antiemorragica. Progr. Med. (Napoli) 29, 805.Google Scholar
  8. Lampugnani A. and Cultrera G. (1970) Effect of Bothrops Jararaca venom coagulant fraction on fibrinogen turnover. Farmaco, Ed. sci. 25, 985.Google Scholar
  9. Leroy G. (1965) Contribution à l’étude expérimentale des propriétés de la fraction coagulante P33 du venin de Bothrops jararaca. Doctoral thesis, Paris.Google Scholar
  10. Marti TH. (1975) Zur praktischen Anwendung der blutgerinnenden Wirkung der Botropase. Praxis 64, 1323.Google Scholar
  11. Nicoucar G. (1975) L’utilisation prophylactique et thérapeutique de la Botropase en Chirurgie ORL. Méd. et Hyg. (Genève) 33, 772.Google Scholar
  12. Ottoboni A. and Ciurlo E. (1957) Azione del veleno di Bothrops Jararaca come coagulante in O.R.L. Minerva otorinolaring 7, 4.Google Scholar
  13. Peck S. and Morris-Goldberger A. (1933) The treatment of uterine bleeding with snake venom. Amer. J. Obstet. Gynec. 25, 887.Google Scholar
  14. Pescetto G. and Malagamba G. (1959) Sul meccanismo di azione del veleno di Bothrops Jararaca e sulle sue indicazioni in campo ginecologico. Haematologica 173.Google Scholar
  15. Stocker K. and Sträub P.W. (1970) Rapid detection of fibrinopeptides by bidimentional paper electrophoresis. Thrombos. Diathes. haemorrh. (Stuttg.) 24, 248.Google Scholar

Copyright information

© Martinus Nijhoff, P.O.B. 442, The Hague, The Netherlands 1977

Authors and Affiliations

  • M. Verstraete
    • 1
  1. 1.Department of Medical ResearchUniversity of LeuvenBelgium

Personalised recommendations