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Report on adrenochrome monosemicarbazide (carbazochrome) and carbazochrome salicylate

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Haemostatic Drugs

Abstract

Adrenochrome is an oxidation product of adrenaline (epinephrine) as shown by Green and Richter (1937). Both compounds are unstable, but Braconier et al. (1943) found that when adrenochrome is combined with monosemicarbazone the resulting compound adrenochrome monosemicarbazide (carbazochrome) is stable. This substance is poorly soluble but becomes much more soluble in the form of a sodium salicylate complex and can be given by intramuscular injection or orally. The official name for this compound is carbazochrome salicylate.

Adona AC-17®, Adrenoxyl®, Emex®.

Adrenosem®.

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© 1977 Martinus Nijhoff, P.O.B. 442, The Hague, The Netherlands

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Verstraete, M. (1977). Report on adrenochrome monosemicarbazide (carbazochrome) and carbazochrome salicylate. In: Haemostatic Drugs. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-1106-8_15

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  • DOI: https://doi.org/10.1007/978-94-010-1106-8_15

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-247-2020-0

  • Online ISBN: 978-94-010-1106-8

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