Abstract
We demonstrate the use of dielectrophoresis (DEP) in a programmable microsystem to drive the formation and handling of small (10 to 1000 nL) droplets of sample and reagent on a channel-less, planar reaction surface. DEP-controlled metering and mixing of reagent droplets is shown in a proof-of-principle protein concentration assay. The electronically reconfigurable droplet processor described here is expected to provide functionality for many chemical, biological, and diagnostic applications.
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References
Pohl, H.A. Dielectrophoresis. Cambridge University Press, New York (1978).
Gascoyne, P.R.C., Huang, Y., Pethig, R., Vykoukal, J. & Becker, F. F. Dielectrophoretic separation of mammalian cells studied by computerized image analysis. Meas. Sci. Technol. 3, 439–445 (1992).
Jones, T.B., Gunji, M., Washizu, M. & Feldman, M.J. Dielectrophoretic liquid actuation and nanodroplet formation. J. Appl. Phys. 89, 1441 (2001).
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© 2001 Springer Science+Business Media New York
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Vykoukal, J., Schwartz, J.A., Becker, F.F., Gascoyne, P.R.C. (2001). A Programmable Dielectrophoretic Fluid Processor for Droplet-Based Chemistry. In: Ramsey, J.M., van den Berg, A. (eds) Micro Total Analysis Systems 2001. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-1015-3_25
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DOI: https://doi.org/10.1007/978-94-010-1015-3_25
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-3893-5
Online ISBN: 978-94-010-1015-3
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