Treatment in The Early Stages of Psychosis

Essay Concerning Treatment of a “Moving Target”
  • Jan Libiger
Part of the NATO Science Series book series (ASID, volume 91)


The paper was originally intended to discuss the treatment of early schizophrenia. However, the mention of first episode schizophrenia was avoided and replaced by “early stages of psychosis”. The reason was that it is better to avoid assuming knowledge that we do not possess. What are the boundaries of the disease concept we call schizophrenia? When does it really begin? In the history of psychiatry, the diagnosis of schizophrenia was given to patients with different psychopathology and different courses of the disorder. Different treatment modalities may be required for treating various aspects of psychopathology. The success in controlling positive symptoms of schizophrenia may lead to deterioration of other, less conspicuous psychopathology, e.g. negative or cognitive symptoms.


Negative Symptom Atypical Antipsychotic Receptor Occupancy Extrapyramidal Side Effect Early Response Gene 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Jan Libiger
    • 1
  1. 1.Psychiatric Center PraguePragueCzech Republic

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