Abstract
DNA is a promising construction material for the engineering of artificial nanostractured devices [1]. One of possible DNA implications in bionanodevices is detecting of metal ions. This possibility is based on the fact that metal ions may preferentially bind to definite DNA conformation and thus metal ion binding may give rise to transition between A-, B-, or Z-DNA [2]. Another approach based on utilizing the specific DNA sequence required to detect specific metals was reported recently [3]. In this method single-stranded DNA forms “pocket” that accepts only lead ions. Here we consider a potential DNA-based sensor detecting metal ions which is based on the phenomenon of DNA condensation.
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Teif, V.B., Lando, D.Y. (2001). DNA Condensation Caused by Ligand Binding May Serve as a Sensor. In: Elwenspoek, M. (eds) Sensor Technology 2001. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0840-2_27
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DOI: https://doi.org/10.1007/978-94-010-0840-2_27
Publisher Name: Springer, Dordrecht
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