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Immunological Aspects of Gastroenterology pp 265–312Cite as

Regulation of intestinal immune responses to local antigens: oral tolerance vs immunopathology

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Part of the book series: Immunology and Medicine Series ((IMME,volume 31))

Abstract

The gut-associated lymphoid tissues (GALT) are the largest in the body and can mount a wide array of different effector mechanisms to counter the continual challenge of potential pathogens. Mobilisation of this powerful battery of responses against food antigens would be undesirable, partly because it would limit their uptake and metabolic usefulness, but more importantly hypersensitivity to foods can produce intestinal pathology, such as that seen in coeliac disease and other food sensitive enteropathies (FSE).

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Authors
  1. A. McI. Mowat
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  1. University of Nottingham and Queen’s Medical Centre, Nottingham, UK

    Y. R. Mahida

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© 2001 Kluwer Academic Publishers

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Mowat, A.M. (2001). Regulation of intestinal immune responses to local antigens: oral tolerance vs immunopathology. In: Mahida, Y.R. (eds) Immunological Aspects of Gastroenterology. Immunology and Medicine Series, vol 31. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0790-0_11

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  • DOI: https://doi.org/10.1007/978-94-010-0790-0_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3852-2

  • Online ISBN: 978-94-010-0790-0

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