Major Cellular Structures Involved in Excitation-Contraction Coupling

  • Donald M. Bers
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 237)


Numerous cellular structures are involved with the process of excitation-contraction coupling (E-C coupling) in cardiac muscle cells. This chapter serves to introduce some of these components from an ultrastructural perspective, and key functional components will be discussed in greater detail in subsequent chapters. Figures 1 and 2 are schematic drawings of the structure of amphibian skeletal muscle (Fig 1) and mammalian ventricular muscle (Fig 2) from a classic ultrastructural study by Fawcett & McNutt (1969; also based on the work of Peachey, 1965).


Permeability Fibril Integrin Cytosol Alkaloid 


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Copyright information

© Springer Science+Business Media Dordrecht 2001

Authors and Affiliations

  • Donald M. Bers
    • 1
  1. 1.Department of PhysiologyLoyola University ChicagoMaywoodUSA

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