Major Cellular Structures Involved in Excitation-Contraction Coupling

  • Donald M. Bers
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 237)


Numerous cellular structures are involved with the process of excitation-contraction coupling (E-C coupling) in cardiac muscle cells. This chapter serves to introduce some of these components from an ultrastructural perspective, and key functional components will be discussed in greater detail in subsequent chapters. Figures 1 and 2 are schematic drawings of the structure of amphibian skeletal muscle (Fig 1) and mammalian ventricular muscle (Fig 2) from a classic ultrastructural study by Fawcett & McNutt (1969; also based on the work of Peachey, 1965).


Sarcoplasmic Reticulum Ryanodine Receptor Thin Filament Thick Filament Purkinje Fiber 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Copyright information

© Springer Science+Business Media Dordrecht 2001

Authors and Affiliations

  • Donald M. Bers
    • 1
  1. 1.Department of PhysiologyLoyola University ChicagoMaywoodUSA

Personalised recommendations