Abstract
Pancreas transplantation is firmly established as an excellent means of achieving euglycemia for selected individuals with type 1 diabetes mellitus [1]. In those patients restoration of autonomous glucose regulation through implantation of a vascularized pancreas abrogates a pre-existing insulinopenia ascribed to auto-immune destruction of native beta-cells. Data on application of this approach to individuals with type 2 diabetes mellitus whose hyperglycemia is caused by relative, not absolute, insulin deficiency is scarce but encouraging. Although 129 type 2 recipients are reported to the International Transplant Registry, they represent only 4% of all registered pancreas transplant recipients [2], while it is estimated that approximately 90% of all American diabetics [3], and 78% of diabetics with endstage renal disease are type 2 [4]. Both graft and patient survival (the standard indicators of successful transplantation) among this small cohort of type 2 pancreas transplant recipients match the registry results of pancreatic allografts in type 1 diabetics [2]. To ascertain whether this limited initial success has altered prior reluctance to proffer pancreas transplantation for type 2 diabetes we conducted a mail survey of American pancreas transplant programs.
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Friedman, A.L., Friedman, E.A. (2002). Prevalent US Transplant Center Policies Towards Pancreas Transplantation for Patients with Type 2 Diabetes Mellitus. In: Friedman, E.A., L’Esperance, F.A. (eds) Diabetic Renal-Retinal Syndrome. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0614-9_16
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DOI: https://doi.org/10.1007/978-94-010-0614-9_16
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