Abstract
Immunological techniques have been used for decades to distinguish among and identify microorganisms and their products. These methods are all based on the ability of antibodies to bind with exquisite specificity to defined structures called antigen epitopes or antigen determinants characteristic of microbial components. The usefulness of immunological assays depends to a large extent on the binding affinity and specificity of the antibodies and how they are coupled to detection systems, which all together determine the sensitivity and facility of the procedures in identifying agents.
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Nixdorff, K. (2002). Molecular Biological Techniques for Subspecies Identification: Immunological Techniques a Comparison. In: Dando, M.R., Klement, C., Negut, M., Pearson, G.S. (eds) Maximizing the Security and Development Benefits from the Biological and Toxin Weapons Convention. NATO Science Series, vol 36. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0472-5_11
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DOI: https://doi.org/10.1007/978-94-010-0472-5_11
Publisher Name: Springer, Dordrecht
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