Abstract
Recently, methods have been developed for the delivery of exogenous proteins into living cells with the help of membrane-permeable carrier peptides such as HIV-1 Tat-(48–60) and Antennapedia-(43–58). By hybridizing these carrier peptides genetically or chemically, efficient intracellular delivery of various oligopeptides and proteins was achieved [1,2]. These methods would become powerful tools not only for therapeutic purposes, but also for the understanding of the mechanisms behind fundamental cellular events, such as signal transduction and gene transcription.
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References
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© 2001 Springer Science+Business Media Dordrecht
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Futaki, S. et al. (2001). Translocation of Various Arginine-Rich Peptides and the Potential of These Peptides as Carriers for Intracellular Protein Delivery. In: Lebl, M., Houghten, R.A. (eds) Peptides: The Wave of the Future. American Peptide Symposia, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0464-0_443
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DOI: https://doi.org/10.1007/978-94-010-0464-0_443
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