Studies on the Involvement of a His Residue of mt1 GPCR TM Helix V in the Interaction with Melatonin
Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a hormone produced mainly by the pineal gland in most vertebrate species, including humans. The physiological role of MLT is related to both chronobiology and modulation of the body’s hormonal milieu. MLT appears to exert these effects through specific high affinity receptors. MLT has also been shown to have powerful antioxidant properties acting as an efficient free radicals scavenger.
KeywordsHPLC Propen MeOH Melatonin Indole