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Studies on the Involvement of a His Residue of mt1 GPCR TM Helix V in the Interaction with Melatonin

  • Andrea Calderan
  • Paolo Ruzza
  • Donata Favretto
  • Barbara Biondi
  • Barbara Scolaro
  • Gianfranco Borin
Part of the American Peptide Symposia book series (APSY, volume 7)

Abstract

Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a hormone produced mainly by the pineal gland in most vertebrate species, including humans. The physiological role of MLT is related to both chronobiology and modulation of the body’s hormonal milieu. MLT appears to exert these effects through specific high affinity receptors. MLT has also been shown to have powerful antioxidant properties acting as an efficient free radicals scavenger.

Keywords

Versus Versus Versus Pineal Gland Phospholipid Vesicle Mass Spectrometry Study Random Coil Structure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 2001

Authors and Affiliations

  • Andrea Calderan
    • 1
  • Paolo Ruzza
    • 1
  • Donata Favretto
    • 2
  • Barbara Biondi
    • 3
  • Barbara Scolaro
    • 3
  • Gianfranco Borin
    • 1
  1. 1.CNR Biopolymers Research CenterPadovaItaly
  2. 2.CNR-TCMETPadovaItaly
  3. 3.Department of Organic ChemistryUniversity of PadovaPadovaItaly

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