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Studies on the Involvement of a His Residue of mt1 GPCR TM Helix V in the Interaction with Melatonin

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Peptides: The Wave of the Future

Part of the book series: American Peptide Symposia ((APSY,volume 7))

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Abstract

Melatonin (N-acetyl-5-methoxytryptamine, MLT) is a hormone produced mainly by the pineal gland in most vertebrate species, including humans. The physiological role of MLT is related to both chronobiology and modulation of the body’s hormonal milieu. MLT appears to exert these effects through specific high affinity receptors. MLT has also been shown to have powerful antioxidant properties acting as an efficient free radicals scavenger.

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Author information

Authors and Affiliations

  1. CNR Biopolymers Research Center, Padova, I-35131, Italy

    Andrea Calderan, Paolo Ruzza & Gianfranco Borin

  2. CNR-TCMET, Padova, I-35100, Italy

    Donata Favretto

  3. Department of Organic Chemistry, University of Padova, Padova, I-35131, Italy

    Barbara Biondi & Barbara Scolaro

Authors
  1. Andrea Calderan
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  2. Paolo Ruzza
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  3. Donata Favretto
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  4. Barbara Biondi
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  5. Barbara Scolaro
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  6. Gianfranco Borin
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Editor information

Editors and Affiliations

  1. Spyder Instruments, Inc. and Illumina, Inc., 9885 Towne Centre Drive, 92121, San Diego, CA, USA

    Michal Lebl

  2. Torrey Pines Institute for Molecular Studies, Mixture Sciences, Inc., 3550 General Atomics Court, 92121, San Diego, CA, USA

    Richard A. Houghten

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© 2001 Springer Science+Business Media Dordrecht

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Calderan, A., Ruzza, P., Favretto, D., Biondi, B., Scolaro, B., Borin, G. (2001). Studies on the Involvement of a His Residue of mt1 GPCR TM Helix V in the Interaction with Melatonin. In: Lebl, M., Houghten, R.A. (eds) Peptides: The Wave of the Future. American Peptide Symposia, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0464-0_395

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  • DOI: https://doi.org/10.1007/978-94-010-0464-0_395

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3905-5

  • Online ISBN: 978-94-010-0464-0

  • eBook Packages: Springer Book Archive

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