Stepwise Peptide-Peptoid Transformation via SPOT Synthesis
Bioactive peptides are promising lead structures for the development of novel drugs. However, peptides have many drawbacks for their direct use as therapeutics such as degradation by proteases and low bioavailability. These limitations can be overcome by their transformation into peptidomimetics.
KeywordsBioactive Peptide Natural Amino Acid Small Organic Compound Substitutional Analysis Remain Amino Acid