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Peptides: The Wave of the Future pp 577–578Cite as

Stepwise Peptide-Peptoid Transformation via SPOT Synthesis

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Part of the book series: American Peptide Symposia ((APSY,volume 7))

Abstract

Bioactive peptides are promising lead structures for the development of novel drugs. However, peptides have many drawbacks for their direct use as therapeutics such as degradation by proteases and low bioavailability. These limitations can be overcome by their transformation into peptidomimetics.

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References

  1. Hahn, M., Winker, D., Welfle, K., Misselwitz, R., Welfle, H., Wessner, H., Zahn, G., Scholz, C., Seifert, M., Hawkins, R., Schneider-Mergener, J., Höhne, W. J. Mol. Biol. 314, 293–309 (2001).

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Author information

Authors and Affiliations

  1. Jerini AG, 12489, Berlin, Germany

    Ulrich Reineke, Thomas Ast, Thomas Polakowski & Jens Schneider-Mergener

  2. Institut für Medizinische Immunologie, Charité, Humboldt-Universität zu Berlin, 10098, Berlin, Germany

    Berit Hoffmann, Thomas Ast, Jens Schneider-Mergener & Rudolf Volkmer-Engert

Authors
  1. Ulrich Reineke
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  2. Berit Hoffmann
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  3. Thomas Ast
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  4. Thomas Polakowski
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  5. Jens Schneider-Mergener
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  6. Rudolf Volkmer-Engert
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Editor information

Editors and Affiliations

  1. Spyder Instruments, Inc. and Illumina, Inc., 9885 Towne Centre Drive, 92121, San Diego, CA, USA

    Michal Lebl

  2. Torrey Pines Institute for Molecular Studies, Mixture Sciences, Inc., 3550 General Atomics Court, 92121, San Diego, CA, USA

    Richard A. Houghten

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© 2001 Springer Science+Business Media Dordrecht

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Reineke, U., Hoffmann, B., Ast, T., Polakowski, T., Schneider-Mergener, J., Volkmer-Engert, R. (2001). Stepwise Peptide-Peptoid Transformation via SPOT Synthesis. In: Lebl, M., Houghten, R.A. (eds) Peptides: The Wave of the Future. American Peptide Symposia, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0464-0_267

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  • DOI: https://doi.org/10.1007/978-94-010-0464-0_267

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3905-5

  • Online ISBN: 978-94-010-0464-0

  • eBook Packages: Springer Book Archive

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