Abstract
Oxygen-linked glycopeptides are vital constituents of biological membranes and their carbohydrate moieties play key role in molecular recognition processes [1]. However, O-glycosidic bonds in these molecules are sensitive to both chemical and enzymatic deglycosylation. Preparation of the hydrolytically more stable C-glycosylated analogs has attracted much attention recently. The objectives of this study were to prepare β-and β-amino acids ß-linked to the carbohydrate moiety as building blocks in combinatorial approaches to generate glycopeptide mimetics by solid phase peptide synthesis methods.
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© 2001 Springer Science+Business Media Dordrecht
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Jablonkai, I. (2001). New Approach for Preparation of C-Glycoamino Acid Building Blocks. In: Lebl, M., Houghten, R.A. (eds) Peptides: The Wave of the Future. American Peptide Symposia, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0464-0_20
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DOI: https://doi.org/10.1007/978-94-010-0464-0_20
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-3905-5
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