DARWINIZER® — a Computer Based Method for Peptide and Peptidomimetics Design

  • Matthias Filter
  • Paul Wrede
Part of the American Peptide Symposia book series (APSY, volume 7)

Abstract

Due to the metabolic instability of peptides, the design of modified isofunctional peptidomimetics is an adequate approach toward their application in pharmacology. DARWINIZER® is a computer-based tool for the de novo design of modified peptide structures. DARWINIZER® is an extension of the PepHarvester® and SME® algorithm [1–3] including non-canonical amino acids.

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Copyright information

© Springer Science+Business Media Dordrecht 2001

Authors and Affiliations

  • Matthias Filter
    • 1
  • Paul Wrede
    • 1
  1. 1.CallistoGen AGHennigsdorfGermany

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