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From Merrifield to MetaPhore: A Random Walk with Serendipity

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Book cover Peptides: The Wave of the Future

Part of the book series: American Peptide Symposia ((APSY,volume 7))

Abstract

It is the highpoint of my career to receive this award, named in honor of my Ph.D. mentor, Bruce Merrifield. There is little that I can add to what we all know regarding the impact that Bruce has had on peptide research. Certainly, he has had a more significant impact on my scientific development than any other individual. I do need, however, to acknowledge from the start that I have made a habit of associating myself with outstanding individuals, such as Bruce, who have made me look good. My mother always advised, “You are known by your friends” and I took those words to heart. I also need to acknowledge the support of my wife Suzanne, our four children and their spouses for their sacrifices and encouragement over the many years. Suzanne and I are in the middle of our 42nd year of marriage. She received a Ph.T. (put husband through) degree from Caltech when I graduated in 1962, and has never wavered in her support. So my thanks to my family, students, postdocs and collaborators for allowing me to be associated with their lives; this award belongs to you collectively.

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References

  1. Marshall, G.R., Merrifield, R.B. Biochemistry 4, 2394–2401, 1965.

    Article  CAS  Google Scholar 

  2. Leznoff, C. Acc. Chem. Res. 11, 327–333, 1978.

    Article  CAS  Google Scholar 

  3. Nemethy, G., Scheraga, H.A. Biopolymers 3, 155–184, 1965.

    Article  CAS  Google Scholar 

  4. Clark, W.A., Molnar, C.E. MD Computing 11, 311–317, 1994.

    CAS  PubMed  Google Scholar 

  5. Barry, C.D., Graesser, S., Marshall, G.R., In Faiman, M., Nievergelt, J. (Eds.) Pertinent Concepts in Computer Graphics, University of Illinois Press, Chicago, 1969.

    Google Scholar 

  6. Marshall, G.R., Bosshard, H.E. Circulation Res. 31 (Suppl. 2), II-143-II-150, 1972.

    PubMed  Google Scholar 

  7. Pietta, P.G., Marshall, G.R. Chem. Commun. 650–651, 1970.

    Google Scholar 

  8. Hancock, W.S., Marshall, G.R., Vagelos, P.R. J. Biol. Chem. 248, 2424–2434, 1973.

    CAS  PubMed  Google Scholar 

  9. Hancock, W.S., Prescott, D.J., Vagelos, P.R., Marshall, G.R. J. Org. Chem. 38, 774–781, 1973.

    Article  CAS  Google Scholar 

  10. Marshall, G.R., Vine, W., Needlemann, P. Proc. Natl. Acad. Sci. U.S.A. 67, 1624–1630, 1970.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  11. Rich, D.H., Sun, C.-Q., Prasad, J.V.N.V., Pathiasseril, A., Toth, M.V., Marshall, G.R., Clare, M., Mueller, R.A., Houseman, K. J. Med. Chem. 34, 1222–1225, 1991.

    Article  CAS  PubMed  Google Scholar 

  12. Ondetti, M.A., Cushman, D.W. Ann. Rev. Biochem. 51, 283–308, 1982.

    Article  CAS  PubMed  Google Scholar 

  13. Wyvratt, M.J., Patchett, A.A. Med. Res. Rev. 5, 483–531, 1985.

    Article  CAS  PubMed  Google Scholar 

  14. Toh, H., Ono, M., Saigo, K., Miyata, T. Nature 315, 691, 1985.

    Article  CAS  Google Scholar 

  15. Toth, M.V., Marshall, G.R. Int. J. Pept. Protein Res. 36, 544–550, 1990.

    Article  CAS  PubMed  Google Scholar 

  16. Toth, M.V., Chiu, F., Glover, G., Kent, S.B.H., Ratner, L., Heyden, N.V., Green, J., Rich, D.H., Marshall, G.R., In Peptides: Chemistry, Structure, and Biology (Proceedings of the 11th American Symposium), ESCOM, Leiden, 1990.

    Google Scholar 

  17. Miller, M., Sathyanarayana, B.K., Wlodawer, A., Toth, M.V., Marshall, G.R., Clawson, L., Selk, L., Schneider, J., Kent, S.B.H. Science 246, 1149–1152, 1989.

    Article  CAS  PubMed  Google Scholar 

  18. Marshall, G.R., Cramer III R.D. Trends Pharmacol. Sci. 9, 285–289, 1988.

    Article  CAS  PubMed  Google Scholar 

  19. DePriest, S.A., Mayer, D., Naylor, C.B., Marshall, G.R. J. Am. Chem. Soc. 115, 5372–5384, 1993.

    Article  CAS  Google Scholar 

  20. Waller, C.L., Oprea, T.I., Giolitti, A., Marshall, G.R. J. Med. Chem. 36, 4152–4160, 1993.

    Article  CAS  PubMed  Google Scholar 

  21. Head, R.D., Smythe, M.L., Oprea, T.I., Waller, C.L., Green, S.M., Marshall, G.R. J. Am. Chem. Soc. 118, 3959–3969, 1996.

    Article  CAS  Google Scholar 

  22. Dratz, E.A., Furstenau, J.E., Lambert, C.G., Thireault, D.L., Rarick, H., Schepers, T., Pakhlevaniants, S., Hamm, H.E. Nature 363, 276–281, 1993.

    Article  CAS  PubMed  Google Scholar 

  23. Dratz, E.A., Furstenau, L.E., Lambert, C.G., Thireault, D.L., Rarick, H., Schepers, T., Pakhlevaniants, S., Hamm, H.E. Nature 390, 424, 1997.

    Article  CAS  Google Scholar 

  24. Kisselev, O.G., Kao, J., Ponder, J.W., Fann, Y.C., Gautam, N., Marshall, G.R. Proc. Natl. Acad. Sci. U.S.A. 95, 4270–4275, 1998.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  25. Marshall, G. R., Ragno, R., Makara, G.M., Arimoto, R., Kisselev, O. Lett. Peptide Sci. 6, 283–288, 1999.

    CAS  Google Scholar 

  26. Arimoto, R., Kisselev, O.G., Makara, G.M., Marshall, G.R. Biophys. J. (2001), submitted.

    Google Scholar 

  27. Riley, D.P. Adv. Supramol. Chem. 6, 217–244, 2000.

    Article  CAS  Google Scholar 

  28. Aston, K.W., Henke, S.L., Modak, A.S., Riley, D.P., Sample, K.R., Weiss, R.H., Neumann, W.L. Tetrahedron Lett. 35, 3687–3690, 1994.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Biochemistry and Molecular Biophysics, Washington University, St. Louis, MO, 63110, USA

    Garland R. Marshall

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  1. Garland R. Marshall
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Editor information

Editors and Affiliations

  1. Spyder Instruments, Inc. and Illumina, Inc., 9885 Towne Centre Drive, 92121, San Diego, CA, USA

    Michal Lebl

  2. Torrey Pines Institute for Molecular Studies, Mixture Sciences, Inc., 3550 General Atomics Court, 92121, San Diego, CA, USA

    Richard A. Houghten

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© 2001 Springer Science+Business Media Dordrecht

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Marshall, G.R. (2001). From Merrifield to MetaPhore: A Random Walk with Serendipity. In: Lebl, M., Houghten, R.A. (eds) Peptides: The Wave of the Future. American Peptide Symposia, vol 7. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0464-0_1

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  • DOI: https://doi.org/10.1007/978-94-010-0464-0_1

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-3905-5

  • Online ISBN: 978-94-010-0464-0

  • eBook Packages: Springer Book Archive

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