Study of the Activity and Stereoselectivity of Some Metathesis Catalysts with Acyclic Internal Olefins
The stereochemistry of the olefin metathesis has been the subject of numerous publications which tried to rationalize the behaviour of various catalysts with acyclic olefins [1-5]. It had been noticed during these studies that a cis olefin gave preferentially a cis olefin and that a trans olefin led essentially to a trans olefin. This was explained in terms of stability of the metallacyclobutanes involved in the catalytic cycle (Scheme 1): the most favoured metallacyclobutanes are those where the substituents in positions 1 and 3 are equatorial. This simple rule allowed the explanation of most experimental results and the configuration retention.
KeywordsCatalytic Cycle Metathesis Reaction Olefin Metathesis Ring Opening Metathesis Grubbs Catalyst
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