A study unable to find a difference is not the same as an equivalent study. For example, a study of 3 subjects does not find a significant difference simply because the sample size is too small. Equivalence testing is particularly important for studying the treatment of diseases for which a placebo control would unethical. In the situation a new treatment must be compared with standard treatment. The latter comparison is at risk of finding little differences.
KeywordsEquivalence Study Placebo Control Equivalence Testing Equivalence Trial Equivalence Range
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