Abstract
Increased intracranial pressure (ICP) is a common complication in patients with acute liver failure that may result in fatal brain damage. Increased ICP and cerebral herniation correlate with high arterial ammonia levels. It has been demonstrated that ammonia may cause cerebral edema by inducing high extracellular glutamate levels in the brain.1
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© 2003 Springer Science+Business Media Dordrecht
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Larsen, M.H., Poulsen, M., Hansen, B.A., Larsen, F.S. (2003). Effect of erythropoietin on intracranial pressure and brain water in rats with hyperammonemia. In: Jones, E.A., Meijer, A.J., Chamuleau, R.A.F.M. (eds) Encephalopathy and Nitrogen Metabolism in Liver Failure. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0159-5_32
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DOI: https://doi.org/10.1007/978-94-010-0159-5_32
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-010-3967-3
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