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Reversal of Fischer’s ratio in an anesthetised porcine model of acute liver failure

  • K. J. Dabos
  • P. N. Newsome
  • J. N. Plevris
  • P. C. Hayes

Abstract

For decades scientists have been experimenting with animal models of fulminant hepatic failure (FHF). They are supposed to provide a controlled experimental environment that is unachievable in clinical practice. An animal model should be reproducible and the species must have metabolic and physiologic pathways similar to those in humans.1

Keywords

Hepatic Encephalopathy Aromatic Amino Acid Acute Liver Failure Fulminant Hepatic Failure Continuous Intravenous Infusion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer Science+Business Media Dordrecht 2003

Authors and Affiliations

  • K. J. Dabos
    • 1
  • P. N. Newsome
    • 1
  • J. N. Plevris
    • 1
  • P. C. Hayes
    • 1
  1. 1.Liver Cell Biology Laboratory, Department of MedicineRoyal Infirmary of EdinburghEdinburghUK

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