Methodological aspect of epidemiological inquiries in clinical radiobiology

  • J. Martin
  • A. Bertrand


The difficulty of epidemiological studies in clinical radiobiology is mainly due to:
  • determination of the dose effectively delivered to all or part of an organism, especially when there is a radioactive link (localisation and percentage of each isotope, fraction of the dose over a period of time);

  • the delay between application of the product and its long-term effects;

  • interaction with the spontaneous course and various treatments;

  • the relative rareness of complications, the patients are treated from an average age of at least 40 years, after verification of the inefficacy of other treatments.


Objective Criterion Epidemiological Inquiry Index System Methodological Aspect Independent Research 
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Copyright information

© ECSC, EEC, EAEC, Brussels-Luxembourg 1978

Authors and Affiliations

  • J. Martin
    • 1
  • A. Bertrand
    • 2
  1. 1.Section d’Informatique et Statistiques MédicalesGroupe INSERM U 115Nancy CedexFrance
  2. 2.Service de Médecine Nucléaire C. H. U. BraboisVandoeuvreFrance

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