Oxygen was discovered in 1774 by Joseph Priestley, who was the first to suggest that breathing oxygen ‘might be salutary to the lungs in certain morbid cases’. The early apparatus for oxygen administration consisted of a rubber tube through which oxygen was delivered to the patient’s mouth. During the 1914–18 war Haldane devised a face piece and valve which prevented waste of oxygen during expiration and allowed the concentration of oxygen to be varied. In 1938 Barach reported the neurological complications of oxygen therapy, which could be prevented by giving low concentrations of oxygen which were gradually increased. It was not until 1960 that E. J. M. Campbell devised a simple and reliable mask which delivered predetermined concentrations of oxygen in the range 24–35% with an accuracy of 2%. Controlled oxygen therapy thus became feasible and, with monitoring of the blood gases, oxygen therapy was placed on a rational basis.
KeywordsChronic Bronchitis Acute Respiratory Failure Oxygen Therapy Chronic Lung Disease Tissue Hypoxia
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