Abstract
A new mutant Sprague Dawley rat is described, in which the occurrence of bilateral nuclear lens opacities with a fusiform or pyramidal connection to the anterior lens pole (cat-b) is a recessively inherited trait. The gene has about 99% penetrance and a slight variation in expression. During lens development the opaque nucleus-pole connection eventually becomes disrupted so that all animals have mere nuclear cataracts, when they reach the age of 100 days. Lens fresh weights are reduced in affected animals under the age of 16 days.
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© 1979 Dr W. Junk b.v. Publishers
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Koch, HR., Baumgarten, H., Kratochvilova, J. (1979). Anterior Fusiform Cataract (Cat-B): A New Type of Recessively Inherited Lens Opacity in the Sprague Dawley Rat. In: Hockwin, O., Rathbun, W.B. (eds) Progress in Anterior Eye Segment Research and Practice. Documenta Ophthalmologica Proceedings Series, vol 18. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9609-0_19
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DOI: https://doi.org/10.1007/978-94-009-9609-0_19
Publisher Name: Springer, Dordrecht
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