Fast Kinetics by NMR: Binding and Release of Cations by Biomolecules

  • J. Grandjean
  • A. Cornelis
  • P. Laszlo
Conference paper
Part of the NATO Advanced Study Institutes Series book series (ASIC, volume 50)


Because of its high sensitivity, sodium-23 nuclear magnetic resonance (NMR) is useful for the study of ion-substrate interactions (1). Complex formation induces a relaxation enhancement of the nuclear spins manifested by line broadening whereas the position of the peak is little affected. Under some conditions, such relaxation measurements can be used to determine the forward and the reverse rate constants for complex formation. In this paper we present examples of the determination of kinetic parameters by NMR.


Nuclear Magnetic Resonance Relaxation Rate Electric Field Gradient Relaxation Measurement Rotational Correlation Time 
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Copyright information

© D. Reidel Publishing Company 1979

Authors and Affiliations

  • J. Grandjean
    • 1
  • A. Cornelis
    • 1
  • P. Laszlo
    • 1
  1. 1.Institut de Chimie Organique B6Université de LiègeLiègeBelgium

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