Abstract
Every living organism from the simplest one to the more complex contains small amounts of metals. The fundamental importance of metal ions in biological processes has become clearer in the last decade. The effects of heavy metal pollution of the environment and the living organisms have started exhaustive studies on the medical and technical aspects of the toxic metals, mercury, lead, etc. These are a few of the most dangerous industrial metal contaminants. However, some metals, in small quantities act as catalysts in very important enzymatic biological reactions. The ferrodoxins, for example, are the most ancient biological iron-catalysts. Hemoglobin, the red substance in the blood, contains iron and is very important for life in uptaking oxygen during respiration. Metal ions are involved in a very large number of reactions and modify either the mechanism of the reaction or its rate, or both.
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References
Helmut Sigel (Ed). Metal ions in biological systems, Vol, 3 Marcel Dekker, inc. New York, 1974, pp 62.
G.L. Eichhorn, Inorganic Biochemistry. Chapts. 33 and 34, Elsevier 1975.
Ei-Ichiro Ochiai, Bioinorganic Chemistry, An introduction, Allyn and Bacon, Inc. Toronto 1977 pp. 18.
S. Ahrland, J. Chatt, and N.R. Davies, Quart. Rev., 12, 265 (1968).
B.L. Vallee and R.J.P. Williams, Proc.Nat. Acad. Sci. (USA) 59. 498 (1968).
P. de Meester, D.M.L. Goodgame, A.C. Spaski, and B.T. Smith Biochem. Biophys. Acta, 340, 113 (1974).
D.M.L. Goodgame, I. Jeeves, F.L. Phillips and A.C. Spaski, Biochem. Biophys. Acta, 378, 153 (1975).
R.W. Geliert and R. Bau, J. Am. Chem. Soc., 97, 7379 (1975).
A. Terzis, N. Hadjiliadis, R. Rivest, and T. Theqphanides, Inorg. Chim. Acta, 12, L5 (1975).
C.J.L. Lock and R.A. Speranzini, J. Am. Chem. Soc., 98, 7865 (1976).
E. Frieden and J. Alles, J. Biol. Chem., 230, 797 (1958).
J.A. Carrabine and M. Sandarilangam, J. Am.Chem. Soc., 92, 369 (1968).
H. Sternlich, R.G. Shulman and E.W. Anderson, J. Chem. Phys. 43, 3123 (1965).
A.T. Tu and C.G. Friederich, Biochemistry, 7, 4367 (1968).
A.T. Tu and Reinosa, Biochemistry, 5, 3375 (1967).
L.E. Minchenkova and V.I. Ivancv, Biopolymers, 5, 615 (1967).
L.N. Drordov-Tikhomirov and L.I. Kikoin, Biofizika, 12, 407 (1967).
P.C. Kong and T. Theophanides, Inorg. Chem. 13, 1167 (1974).
J.P. Macquet and T. Theophanides, Biopolymers, 14, 781 (1975).
J.P. Macquet and T. Theophanides, Bioinorg. Chem., 5, 59 (1975).
M.M. Millard, J.P. Macquet, and T. Theophanides, Biochim. Biophys. Acta, 402, 166 (1975).
(a) E. Sletten, J. Chem. Soc, Chem. Commun., 558 (1971).
E. Sletten, Acta Crystallogr., Sect. B, 30, 1961 (1974).
N. Hadjiliadis and T. Theophanides, Inorg. Chim. Acta, 16, 66, 77 (1976).
G. Pneumatikakis, N. Hadjiliadis and T. Theophanides, Inorg. Chem. 17, 915 (1978).
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© 1979 D. Reidel Publishing Company, Dordrecht, Holland
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Theophanides, T. (1979). Interaction of Metal Ions with Nucleic Acids. In: Theophanides, T.M. (eds) Infrared and Raman Spectroscopy of Biological Molecules. Nato Advanced Study Institutes Series, vol 43. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9412-6_16
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DOI: https://doi.org/10.1007/978-94-009-9412-6_16
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