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Conformational Studies on Synthetic Polypeptides. Contribution to the Optical Activity from Side-Chain Chromophores

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Optically Active Polymers

Part of the book series: Charged and Reactive Polymers ((CHRP,volume 5))

Abstract

Studies on the chiroptical properties of polypeptides containing aromatic side-chain chromophores are in general complicated by strong overlapping contributions from peptide and side-chain chromophores. Nevertheless such investigations are essential in order to know the details of the aromatic contributions to the optical activity as related to the structure, especially in connection with aromatic Cotton effects observed in CD spectra of proteins. The CD bands associated with tyrosyl-, tryptophanyl-, histidyl-, and phenyl- alanyl-residues in proteins are very sensitive probes of local conformations and could yield valuable structural information.

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Author information

Authors and Affiliations

  1. Institute of Organic Chemistry, University of Padova, Via Mazolo 1, 35100, Padova, Italy

    E. Peggion, A. Cosani, M. Terbojevich & M. Palumbo

Authors
  1. E. Peggion
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  2. A. Cosani
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  3. M. Terbojevich
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  4. M. Palumbo
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Editor information

Editors and Affiliations

  1. Université de Rouen, France

    Eric Selegny

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© 1979 D. Reidel Publishing Company

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Peggion, E., Cosani, A., Terbojevich, M., Palumbo, M. (1979). Conformational Studies on Synthetic Polypeptides. Contribution to the Optical Activity from Side-Chain Chromophores. In: Selegny, E. (eds) Optically Active Polymers. Charged and Reactive Polymers, vol 5. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9378-5_11

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  • DOI: https://doi.org/10.1007/978-94-009-9378-5_11

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-9380-8

  • Online ISBN: 978-94-009-9378-5

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