Abstract
The immune response may be either referred to cellular or to humoral immunity in cerebrospinal fluid (CSF) as in all other biological fluids. The study of cellular immunity in CSF has never been thoroughly undertaken, however, recent work has brought important information in this field, and allowed to identify the T lymphocytes (1).
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References
Kam-Hansen, S: Active T cells in blood and CSF in MS and controls. In: Humoral Immunity in Neurological Diseases, Karcher D, A Lowenthal, D Strosberg (Eds), Plenum Press, London, 1979, (in press).
Lowenthal, A: Agar gel electrophoresis in neurology, Elsevier Publishing Co., Amsterdam, 1964.
Sandberg-Wollheim, M: Immunoglobulin synthesis in vitro by cerebrospinal fluid cells in patients with multiple sclerosis. Scand J Immunol 3: 717–730, 1974.
Sandberg-Wollheim, M: Immunoglobulin synthesis in vitro by cerebrospinal fluid cells in patients with meningoencephalitis of presumed viral origin, Scand J Immunol 4: 617–622, 1975.
Vandvik, B, JB Natvig, D Wiger: IgG 1 subclass restriction of oligoclonal IgG from cerebrospinal fluids and brain extracts in patients with multiple sclerosis and subacute encephalitides, Scand J Immunol 5, 427–436, 1976.
Ehrenkranz, NJ, ES Zemel, C Bernstein, K Slater: Immunoglobulin M in the cerebrospinal fluid of patients with arbovirus encephalitis and other infections of the central nervous system. Neurology 24: 976–980, 1974.
Schuller, E, N Delasnerie, M Hélary, M Lefèvre: Serum and cerebrospinal fluid IgM in 203 neurological patients. Eur Neurol 17: 77–82, 1978.
Nerenberg ST, R Prasad, ME Rothman: Cerebrospinal fluid, IgG, IgA, IgM, IgD, and IgE levels in central nervous system disorders. Neurology 28: 988–990, 1978.
Ziola B, T Vuorimaa, A Salmi, M Pancluis, P Halonen, T Arnadottir, G Enders: Measles IgM antibody persistence: Is it a marker for chronic measles virus infections? Acta Neurol Scand 57, suppl 67: 237–238, 1978.
Sindic C, C Cambiaso, PL Masson, EC Laterre: Determination of IgM in the cerebrospinal fluid by particle counting immunoassay (PACIA). In: Humoral Immunity in Neurological diseases, Karcher D, A Lowenthal, D Strosberg (Eds), Plenum Press, London, 1979, (in press).
Olsson JE, H Link: Immunoglobulin abnormalities in multiple sclerosis. Arch Neurol 28: 392–399, 1973.
Mingioli ES, W Strober, WW Tourtellotte, JN Whitaker, DE McFarlin: Quantitation of IgG, IgA and IgM in the CSF by radioimmunoassay. Neurology 28: 991–995, 1978.
Nordal HJ, B Vandvik, E Norrby: Oligoclonal virus antibodies in healthy adults and neurological patients. In: Humoral Immunity in Neurological Diseases, Karcher D, A Lowenthal, D Strosberg (Eds), Plenum Press, London, 1979, (in press).
Lowenthal A, K Adriaenssens, B Colfs, D Karcher, R Van Heule: Oligoclonal gammapathy in ataxia telangiectasia. Z,Neurol 202: 58–63, 1972.
Strosberg AD, D Karcher, A Lowenthal: Structural homogeneity of human subacute sclerosing panencephalitis antibodies. J Immunol 115, 157–160, 1975.
Karcher D, G Matthyssens, A Lowenthal: Isolation and characterization of IgG globulins in subacute sclerosing panencephalitis. Immunology 23: 93–99, 1972.
Strosberg AD, D Karcher, A Lowenthal: Structure and idiotype of human homogeneous antibodies. Immunology 4249, Fed. Proc 969, 1975.
Frick E, L Scheid-Seydel: Untersuchungen mit 1131 markiertem y -Globulin zur Frage der Abstammung der Liquoreiweisskörper. Klin Wschr 36: 857–863, 1958.
Cutler RWP, GV Walters, CF Barlow: 125I-labelled protein in experimental brain oedema. Arch Neurol 11, 225–238, 1964.
Schuller E: Cerebrospinal fluid immunoglobulins. II. Variations in different pathological situations. La nouvelle presse médicale 8: 427–432, 1979.
Tourtellotte WW: Cerebrospinal fluid in Multiple Sclerosis. In: Handbook of Clinical Neurology, Vinken PJ, GW Bruyn (Eds), North Holland Pub, Amsterdam, 1970, p 324–382.
Karcher D, M Noppe, A Lowenthal: A heat stable serum inhibitor of an antigen antibody reaction of subacute sclerosing panencephalitis. J Neurol 261/1: 51–56, 1977.
Bollengier F, A Lowenthal, N Henrotin: Bound and free light chains in SSPE and MS serum and CSF. Z klin Chem 13: 305–310, 1975.
Masson PL: Circulating immune complexes in neurological disorders. In: Humoral Immunity in Neurological Diseases. Karcher D, A Lowenthal, D Strosberg (Eds), Plenum Press, London, 1979, (in press).
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© 1979 ECSC, EEC, EAEC, Brussels-Luxembourg
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Lowenthal, A., Karcher, D. (1979). Immune Responses in the Cerebrospinal Fluid. In: Tyrrell, D.A.J. (eds) Aspects of Slow and Persistent Virus Infections. New Perspectives in Clinical Microbiology, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9339-6_14
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DOI: https://doi.org/10.1007/978-94-009-9339-6_14
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