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Oral Sorbents as Adjunctive Treatment in Uremia

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Replacement of Renal Function by Dialysis

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Abstract

In early 1978, more than 42,000 Americans were sustained by maintenance hemodialysis at an annual cost for the nation in excess of 1100 million dollars. Elsewhere in this book are considerations of the benefits and limitations of the suboptimal correction of uremia permitted by dialytic therapy. There is substantial reason to attempt to shorten the duration and (or) lessen the frequency of regular hemodialysis treatments. A reduction of two hours from each dialysis, for example, might lower overall dialysis cost in the USA by about 200 million dollars while permitting increased patient’s working capabilities. Among the investigational approaches to reduce dialysis duration is the attempt to exploit the intestine’s ability to transfer nitrogenous solutes from blood to lumen. If such flux contains significant quantities of the “right” compounds then intermittent removal by lavage or adsorption would have clinical importance.

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Authors
  1. Eli A. Friedman
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Editor information

Editors and Affiliations

  1. Department of Medicine, University of Amsterdam, Netherlands

    William Drukker M.D. (Formerly Reader in Dialysis Emeritus Director) (Formerly Reader in Dialysis Emeritus Director)

  2. Department of Nephrology and Dialysis, St. Lucas Hospital, Amsterdam, The Netherlands

    William Drukker M.D. (Formerly Reader in Dialysis Emeritus Director) (Formerly Reader in Dialysis Emeritus Director)

  3. 75 De Lairessestreet, 1071 NV, Amsterdam, The Netherlands

    William Drukker M.D. (Formerly Reader in Dialysis Emeritus Director) (Formerly Reader in Dialysis Emeritus Director)

  4. Renal Research Unit, Wellcome Wing, The General Infirmary at Leeds, LS1 3EX, Leeds, UK

    Frank M. Parsons B.Sc., M.D., F.R.C.P. Ed. (Consultant Physician Senior Clinical Lecturer in Renal Medicine) (Consultant Physician Senior Clinical Lecturer in Renal Medicine)

  5. University of Leeds, UK

    Frank M. Parsons B.Sc., M.D., F.R.C.P. Ed. (Consultant Physician Senior Clinical Lecturer in Renal Medicine) (Consultant Physician Senior Clinical Lecturer in Renal Medicine)

  6. Health Center, University of Connecticut, 06032, Farmington, CT, USA

    John F. Maher M.D., F.A.C.P. (Professor of Medicine, Director Division of Nephrology) (Professor of Medicine, Director Division of Nephrology)

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© 1979 Martinus Nijhoff Publishers bv, The Hague

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Friedman, E.A. (1979). Oral Sorbents as Adjunctive Treatment in Uremia. In: Drukker, W., Parsons, F.M., Maher, J.F. (eds) Replacement of Renal Function by Dialysis. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9327-3_13

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  • DOI: https://doi.org/10.1007/978-94-009-9327-3_13

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-90-247-2227-3

  • Online ISBN: 978-94-009-9327-3

  • eBook Packages: Springer Book Archive

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