Abstract
Express dynamic electroretinography (EDERG) and chronoperimetry (CP) were performed before and after the treatment in patients at a proliferative stage of diabetic retinopathy. Laser coagulation or Peritol therapy were used in the treatment. Since the therapeutic effect was found in relation to the ERG type, the authors concluded that ERG might help in prognosis and in the selection of the therapy methods.
Laser coagulation is frequently used in the treatment of diabetic retinopathy. Recently, medicamentous treatment with serotonin antagonists (Peritol, EGYT, Hungary) was initiated, for in this disease excessive accumulation of serotonin takes place on the retina (Quickel, 1971). As can be read from the relevant publications, the ERG amplitude after laser coagulation is reduced. The influence of limited laser coagulation on the functional state of retinal regions, not previously submitted to coagulation and on the optic nerve fibers conduction is not clear, the same as the beneficial effect of laser coagulation in diabetic retinopathy (Apple et al., 1976). And there is still little known about the influence of the antiserotonin line of drugs such as Peritol. In this paper we shall try to answer these questions with the help of some new adequate methods of investigation.
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Nemtseev, H.J., Mikhailova, N.A., Makarskaya, N.V., Katsnelson, L.A., Forofonova, T.I., Sabaeva, G.F. (1980). Electroretinography and Chronoperimetry in Treatment of Diabetic Retinopathy by Drugs and Light Coagulation. In: Schmöger, E., Kelsey, J.H. (eds) Visual Electrodiagnosis in Systemic Diseases. Documenta Ophthalmologica Proceeding Series, vol 23. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9180-4_7
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DOI: https://doi.org/10.1007/978-94-009-9180-4_7
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