Logistic Function in the Analysis of the ERG in Dialysed Patients

  • J. Svérák
  • J. Peregrin
  • D. Hejcmanová
  • J. Erben
  • J. Groh
Part of the Documenta Ophthalmologica Proceeding Series book series (DOPS, volume 23)

Abstract

The ERG intensity-response function of the b-wave in 32 patients undergoing regular hemodialysis treatment was evaluated using a logistic equation. Statistically significant lowering of the retinal sensitivity (M-parameter of the logistic function) has been observed. 37.5% of the patients displayed the subnormal values of the b-waves (A), lower slope (S) and significant lower retinal sensitivity (M). The immediate effect of a single dialysis manifests itself in about 30 per cent of the patients by a transient, statistically significant lowering of the retinal sensitivity.

There is an increasing amount of evidence suggesting that the ERG of patients undergoing the regular hemodialysis treatment is pathologically changed (1, 3, 5). Our previous experience (4) showed that a depressed retinal activity in these patients manifested itself by the depression of the ERG intensity-response curves. The aim of the present study is a detailed quantitative analysis of the ERG intensity-response function.

Keywords

Filtration Depression Xenon Nephritis Glomerulonephritis 

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References

  1. 1.
    Mihara, A. The studies on the eyes of the subjects of renal disease with the treatment by the hemodialysis and the peritoneal dialysis. Report II. The correlation between the EOG and ERG. Acta Soc. Ophthal. Jap. 77: 1116–1123 (1973).PubMedGoogle Scholar
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    Perossini, M. & G. Tota. Electroretinographic findings in chronic uraemics treated with periodic haemodialysis. Docum. Ophthal., Proc. Series, 15: 257–263 (1978).Google Scholar
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    Svěrák, J., J. Peregrin, J. Groh, J. Erben & D. Hejcmanová. Změny elektrické aktivity sítnice při chronické intermetentní dialyze Čs. oftal., 35: 332–338 (1979).Google Scholar
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Copyright information

© Dr W. Junk by Publishers 1980

Authors and Affiliations

  • J. Svérák
    • 1
  • J. Peregrin
    • 1
  • D. Hejcmanová
    • 1
  • J. Erben
    • 1
  • J. Groh
    • 1
  1. 1.Dept. of OphthalmologyUniversity HospitalCzechoslovakia

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