Abstract
Linear-free energy relationships such as the Hammett equation are based upon electronic inductive effects of substituents on a basic site. Simple empirical equations produce calculated values for equilibrium constants which are in satisfactory agreement with the experimental data and which have a useful predicting power for other compounds.
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Braibanti, A. (1980). Enthalpy, Free-Energy, and Entropy Data for Structure-Activity Relationships in Acids and Bases. In: Braibanti, A. (eds) Bioenergetics and Thermodynamics: Model Systems. NATO Advance Study Institutes Series, vol 55. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-9035-7_11
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DOI: https://doi.org/10.1007/978-94-009-9035-7_11
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