Metastasis pp 260-265 | Cite as

Immune Regression of Metastases Following Hyperthermic Treatment of Primary Tumours

  • J. A. Dickson
  • S. K. Calderwood
  • S. A. Shah
  • A. C. Simpson
Part of the Developments in Oncology book series (DION, volume 4)


In the present renewal of interest in the use of hyperthermia (temperatures ≥ 42°C) for the treatment of cancer, a striking finding has been the disappearance of established metastases with host cure following effective heating of the primary tumour. This was first reported by Strauss for the Brown-Pearce carcinoma in the rabbit, and we have confirmed the occurrence of this phenomenon (the ‘abscopal’ response) for 3 different rat tumours and 2 strains of rabbit tumour, encompassing both allogeneic and syngeneic systems (Table 1).


Tumour Blood Flow Curative Heating HYPERTHERMIC Treatment Host Cure Hyperthermic Perfusion 
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Copyright information

© Springer Science+Business Media Dordrecht 1980

Authors and Affiliations

  • J. A. Dickson
  • S. K. Calderwood
  • S. A. Shah
  • A. C. Simpson

There are no affiliations available

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