Abstract
The prognosis for children with acute lymphoblastic leukaemia (ALL) has improved considerably since the introduction of CNS leukaemia prophylaxis by cranial irradiation and intrathecal administration of methotrexate (Mauer and Simone, 1976; Pinkel, 1979). The incidence of CNS-relapses dropped from 50% to approximately 5% of the children. Little is known about the efficacy of this treatment in adults, in whom CNS relapses are also frequent (Willemze et al., 1975; 1979; Gee et al., 1976; Lister et al., 1978.,Pavlovsky et al 1973).
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© 1980 Martinus Nijhoff Publishers bv, The Hague
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Willemze, R., Drenthe-Schonk, A.M., van Rossum, J., Haanen, C. (1980). CNS-Leukaemia Prophylaxis in Adult Acute Lymphoblastic Leukaemia. In: Ongerboer de Visser, B.W., Bosch, D.A., van Woerkom-Eykenboom, W.M.H. (eds) Neuro-Oncology. Developments in Oncology, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8919-1_15
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DOI: https://doi.org/10.1007/978-94-009-8919-1_15
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