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An Automated Chromogenic Antithrombin III Method : Clinical Experience

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Synthetic Substrates in Clinical Blood Coagulation Assays

Part of the book series: Developments in Hematology ((DIHI,volume 1))

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Abstract

Since 1978 an automated chromogenic method for ant ¡thrombin III (AT III) has been applied in various clinical situations in our laboratory (1).

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References

  1. Kahlé LH, Schipper HG, Jenkins CSP, and Ten Cate JW. 1979. An automated method for the determination of antithrombin I I I activity. Thromb.Res. 2, 1003–1014.

    Google Scholar 

  2. Abildgaard U. 1979. Evidence that antithrombin III is the main physiological inhibitor of coagulation enzymes. In: The physiological inhibitors of blood coagulation and fibrinolysis, Collen D, Wiman B, and Verstraete M (Eds.), Elsevier/North-Hol land, Biomedical Press, pp 31–33.

    Google Scholar 

  3. Egeberg O. 1965. Inherited antithrombin deficiency causing thrombophilia. Thromb. Diath. Haemorrh. 13, 516–530.

    PubMed  CAS  Google Scholar 

  4. Sas G, Blaskö G, Bänhegyi D, Jäkö J, and Pälos LA. 1974. Ab¬normal antithrombin III ( Antithrombin III “Budapest”) as a cause of familial thrombophilia. Thromb.Diath.Haemorrh. 32, 105–115.

    PubMed  CAS  Google Scholar 

  5. Schipper HG, Roos J, V.d. Meulen F, and Ten Cate JW. 1980. Antithrombin III deficiency in surgical intensive care patients. Submitted for publication.

    Google Scholar 

  6. Tanaka H, Kobayashi N, Takeuchi T, Takada M, and Malkawa T. 1979. Effect of endotoxin on kinetics of antithrombin III. Thromb.Haemostas. 42, 374.

    Google Scholar 

  7. Büller HR, Weenink AH, Treffers PE, Kahle LH, Otten HA, and Ten Cate JW. 1980. Severe antithrombin III deficiency in a patient with pre-ecclampsia. Scand.J.Haemat. In Press.

    Google Scholar 

  8. Weenink HG, Treffers PE, and Ten Cate JW. 1980. AT III and oral contraceptive therapy. Submitted for publication.

    Google Scholar 

  9. Tytgat GN, Collen D, and Verstraete M. 1971. Metabolism of fibrinogen in cirrhosis of the liver. J.C I i n. I nvest. 50, 1690–1701.

    Article  CAS  Google Scholar 

  10. Collen D, Rouvier J, Chamone DAF, and Verstraete M. 1978. Turnover of radiolabeled plasminogen and prothrombin in cirrhosis of the liver. Eur. J.CI in. I nvest. 8, 185–195.

    Article  CAS  Google Scholar 

  11. Schipper HG and Ten Cate JW. 1980. Antithrombin III transfusion in patients with liver cirrhosis. In: Thesis, University of Amsterdam, Schipper HG: Antithrombin III and human antithrombin III concentrates, pp 65–85.

    Google Scholar 

  12. Giles AR, Sauder D, Seaton TL, Johnston M, and Hirsh J. 1977. Changes in the coagulation status of patients undergoing auto- transfusion of concentrated ascitic fluid as treatment of refractory ascites. Blood 50, 267.

    Google Scholar 

  13. Kauffmann RH, De Graeff J, and Brutel de la Riviere G. 1976. Unilateral thrombosis and nephrotic syndrome. Am.J.Med. 60, 1048–1054.

    Article  PubMed  CAS  Google Scholar 

  14. Kauffman.n. RH, Veitkamp JJ, Van Tilburg NH, and Van Es LA. 1978. Acquired antithrombin III deficiency and thrombosis in the nephrotic syndrome. Am.J.Med. 65, 607–613.

    Article  PubMed  CAS  Google Scholar 

  15. Thaler E, Balzar E, Kopsa H, and Pinggera WF. 1978. Acquired antithrombin III deficiency in patients with glomular proteinuria. Haemostasis 7, 257–272.

    PubMed  CAS  Google Scholar 

  16. Jørgensen KA and Stoffersen E. 1979. Antithrombin I I I and the nephrotic syndrome. Scand.J.Haematol. 22, 442–448.

    Article  PubMed  Google Scholar 

  17. Marciniak E and Gockerman JP. 1977. Heparin-induced decrease in circulating antithrombin III. Lancet 2, 581–584.

    Article  PubMed  CAS  Google Scholar 

  18. Kakkar VV, Bentley PG, Scully MF, MacGregor IR, Jones NAG, and Webb PJ. 1980. Antithrombin III and heparin. Lancet 1, 103–104.

    Article  PubMed  CAS  Google Scholar 

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© 1980 Martinus Nijhoff Publishers bv, The Hague

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Ten Cate, J.W. (1980). An Automated Chromogenic Antithrombin III Method : Clinical Experience. In: Lijnen, H.R., Collen, D., Verstraete, M. (eds) Synthetic Substrates in Clinical Blood Coagulation Assays. Developments in Hematology, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8910-8_5

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  • DOI: https://doi.org/10.1007/978-94-009-8910-8_5

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-8912-2

  • Online ISBN: 978-94-009-8910-8

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