Skip to main content
SpringerLink
Log in
SpringerLink
Log in

The Ni-Hon-San Study of Cardiovascular Disease Epidemiology

Population characteristics and epidemiology of stroke

  • Chapter
Epidemiology of Arterial Blood Pressure

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 8))

Abstract

International data show marked geographic variability in mortality from coronary heart disease (CHD)[1]. Mortality in the United States is among the highest and that in Japan is among the lowest reported. The determination of reasons for these marked differences is made difficult by confounding genetic, environmental, and cultural variation and by the differences in diagnostic techniques and reporting practices used in various countries. One of the methods that has been found useful in overcoming some of these difficulties is the study of migrant populations [2]. Large numbers of Japanese migrated to Hawaii and California late in the 19th century and early in the 20th century. Gordon reported a gradient of CHD mortality with men of Japanese ancestry living in the United States experiencing risks that were intermediate between the low levels in Japan and the high levels among Caucasian Americans [3,4]. Gordon also demonstrated a gradient of increasing CHD mortality among Japanese men in Japan, Hawaii, and California. The gradient of mortality from cerebrovascular disease was the reverse.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Report of Inter-Society Commission for Heart Disease Resources: Primary prevention of the atherosclerotic diseases. Circulation 42:A55–A95, 1970.

    Google Scholar 

  2. Reid DD: The future of migrant studies. Isr J Med Sci 7:1592–1596, 1971.

    PubMed  CAS  Google Scholar 

  3. Gordon T: Mortality experience among the Japanese in the United States, Hawaii and Japan. Public Health Rep 72:543–553, 1957.

    PubMed  CAS  Google Scholar 

  4. Gordon T: Further mortality experience among Japanese Americans. Public Health Rep 82:973–984, 1967.

    PubMed  Google Scholar 

  5. Belsky JL, Kagan A, Syme SL: Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California. Research Plan, Atomic Bomb Casualty Commission Technical Report 12-71, 1971. (Microfiched and stored at: Bay Microfilm, Inc, 737 Loma Verde Avenue, Palo Alto, CA.)

    Google Scholar 

  6. Robertson TL, Shimizu Y, et al.: Incidence of stroke and coronary heart disease in atomic bomb survivors living in Hiroshima and Nagasaki, 1958-74: The Adult Health Study of the Radiation Effects Research Foundation. RERF TR 12–79, 1979.

    Google Scholar 

  7. Belsky JL, Tachikawa K, Jablon S: ABCC-JNIH Adult Health Study, Report 5. Results of the first five cycles of examinations, Hiroshima-Nagasaki 1958–68. Atomic Bomb Casualty Commission Technical Report 9–71, 1971.

    Google Scholar 

  8. Worth RM, Kagan A: Ascertainment of men of Japanese ancestry in Hawaii through World War II Selective Service registration. J Chronic Dis 23:389–397, 1970.

    Article  PubMed  CAS  Google Scholar 

  9. Nichaman MZ, Hamilton HB, Kagan A, Grier T, Sacks ST, Syme SL: Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: Distribution of biochemical risk factors. Am J Epidemiol 102:491–501, 1975.

    PubMed  CAS  Google Scholar 

  10. Rose GA, Blackburn H: Cardiovascular survey methods. Geneva: WHO, 1968.

    Google Scholar 

  11. Kagan A, Popper J, Rhoads GG, Takeya Y, Kato H, Browne Goode G, Marmot M: Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: prevalence of stroke. In: Scheinberg P (ed) Cerebrovascular diseases, 10th Princeton Conference. New York: Raven Press, 1976, pp 267–277.

    Google Scholar 

  12. Robertson TL, Kato H, Rhoads GG, Kagan A, Marmot MG, Syme SL, Gordon T, Worth RM, Belsky JL, Dock DS, Miyanishi M, Kawamoto S: Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: incidence of myocardial infarction and death from coronary heart disease. Am J Cardiol 39:239–243, 1977.

    Article  PubMed  CAS  Google Scholar 

  13. Kagan A, Harris BR, Winkelstein Jr W, Johnson KG, Kato H, Syme SL, Rhoads GG, Gay ML, Nichaman MZ, Hamilton HB, Tillotson JL: Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: demographic, physical, dietary and biochemical characteristics. J Chronic Dis 27:345–364, 1974.

    Article  PubMed  CAS  Google Scholar 

  14. Winkelstein Jr W, Kagan A, Kato H, Sacks ST: Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: blood pressure distributions. Am J Epidemiol 102:502–513, 1975.

    PubMed  Google Scholar 

  15. Health and Welfare Statistics Association: Trends in nation’s health, 1978 (in Japanese). Kosei-no-shihyo 25:380, 1978.

    Google Scholar 

  16. Lin CH, Shimizu Y, Kato H, Robertson TL, Furonaka H, Fukunaga Y: Cerebrovascular disease in a fixed population of Hiroshima and Nagasaki, with special reference to relationship between type and risk factors. RERF Technical Report (in preparation).

    Google Scholar 

  17. Kagan A, Popper JS, Rhoads GG: Factors related to stroke incidence in Hawaii Japanese men: the Honolulu Heart Study. Stroke (in press) 1980.

    Google Scholar 

  18. Worth RM, Kato H, Rhoads GG, Kagan A, Syme SL: Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: Mortality. Am J Epidemiol 102:481–490, 1975.

    PubMed  CAS  Google Scholar 

  19. Mitsuyama Y, Thompson LR, Hayashi Y, Lee KK, Keehn RJ, Steer A: An autopsy study of cerebrovascular disease in Japanese men who lived in Hiroshima, Japan and Honolulu, Hawaii. Stroke (in press) 1980.

    Google Scholar 

  20. Walker SH, Duncan DB: Estimation of the probability of an event as a function of several independent variables. Biometrika 54:167–179, 1967.

    PubMed  CAS  Google Scholar 

  21. Yano K, Rhoads GG, Kagan A: Epidemiology of serum uric acid among 8000 Japanese-American men in Hawaii. J Chronic Dis 30:171–184, 1977.

    Article  PubMed  CAS  Google Scholar 

  22. Insull W, Oiso T, Tsuchiya K: Diet und nutritional status of Japanese. Am J Clin Nutr 21:753–777.

    Google Scholar 

  23. Johnson KG, Yano K, Kato H: Cerebral vascular disease in Hiroshima, Japan. J Chronic Dis 20:545–559, 1967.

    Article  PubMed  CAS  Google Scholar 

  24. Kimura N: Epidemiology of hypertension and stroke in Asia. In: Hatano S, Shigematsu I, Strasser T (eds) Hypertension and stroke control in the community. Geneva: WHO, 1976, pp 55–59.

    Google Scholar 

  25. Komachi Y, Iida M, Ozawa H, Shimamoto T, Konishi M, Ueshima H, Goda N, Furukawa M: Interrelationship of food and stroke in Japan. Ann Rep Cent Adult Dis Osaka 15:82–93, 1975.

    Google Scholar 

  26. Sasaki N, et al.: High blood pressure and the salt intake of the Japanese. Jpn Heart J 3:313–324, 1962.

    Article  PubMed  CAS  Google Scholar 

  27. Yamori Y, Ooshima A: Nutritional prevention of hypertensive diseases. In: Inoue G, Yoshimura H (eds) Effects of alterations of dietary patterns and food habits on health. Osaka, US-Japan Cooperative Medical Sciences Program, 1978, pp 200-209.

    Google Scholar 

  28. Omae T, Takeshita M, Hirota Y: The Hisayama study and joint study on cerebrovascular disease in Japan. In: Scheinberg P (ed) Cerebrovascular diseases, 10th Princeton Conference. New York: Raven Press, 1976, pp 255–265.

    Google Scholar 

Download references

Authors
  1. A. Kagan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. G. Marmot
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Kato
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Cardiology, St.-Rafaël University Hospital, Leuven, Belgium

    H. Kesteloot

  2. Department of Epidemiology, St.-Rafaël University Hospital, Leuven, Belgium

    J. V. Joossens

Rights and permissions

Reprints and permissions

Copyright information

© 1980 Martinus Nijhoff Publishers bv, The Hague/Boston/London

About this chapter

Cite this chapter

Kagan, A., Marmot, M.G., Kato, H. (1980). The Ni-Hon-San Study of Cardiovascular Disease Epidemiology. In: Kesteloot, H., Joossens, J.V. (eds) Epidemiology of Arterial Blood Pressure. Developments in Cardiovascular Medicine, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8893-4_26

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-8893-4_26

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-8895-8

  • Online ISBN: 978-94-009-8893-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation