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Hormonal Control of Prostatic Biochemical Markers: Acid Phosphatase as a Marker of Androgenic Control of the Ventral Prostate

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Prostatic Carcinoma

Part of the book series: Clinics in Andrology ((CLAN,volume 6))

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Abstract

The hormonal dependence of the prostate glands of many species has been extensively studied since the prostate is an integral component of the male reproductive system and because there is a high incidence of pathological processes involving the gland in older men. While a great deal has been learned about the effects and actions of androgens in both prostatic carcinoma and benign prostatic hyperplasia (BPH), detailed studies of the biochemistry of these processes have been hampered by the lack of suitable animal model systems. The two most common animal models used have been the prostates of the dog and rat. In addition several prostatic tumour lines, derived from both rat and dog have been studied recently. However all these systems are morphologically and histologically distinct from the human gland and great care must be taken in extending the findings from these systems to humans.

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Authors
  1. A. F. Clark
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  2. M. P. Tenniswood
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  3. C. E. Bird
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  4. T. G. Flynn
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  5. F. A. Jacobs
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  6. P. A. Abrahams
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Editor information

Editors and Affiliations

  1. Department of Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA

    E. S. E. Hafez

  2. Department of Obstetrics, Wayne State University School of Medicine, Detroit, Michigan, USA

    E. S. E. Hafez

  3. Department of Physiology, Wayne State University School of Medicine, Detroit, Michigan, USA

    E. S. E. Hafez

  4. C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, Detroit, Michigan, USA

    E. S. E. Hafez

  5. Department of Anatomy and Urology, State University of New York, Syracuse, New York, USA

    E. Spring-Mills

  6. Upstate Medical Center, Syracuse, New York, USA

    E. Spring-Mills

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© 1981 Martinus Nijhoff Publishers bv, The Hague

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Clark, A.F., Tenniswood, M.P., Bird, C.E., Flynn, T.G., Jacobs, F.A., Abrahams, P.A. (1981). Hormonal Control of Prostatic Biochemical Markers: Acid Phosphatase as a Marker of Androgenic Control of the Ventral Prostate. In: Hafez, E.S.E., Spring-Mills, E. (eds) Prostatic Carcinoma. Clinics in Andrology, vol 6. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8887-3_8

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  • DOI: https://doi.org/10.1007/978-94-009-8887-3_8

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-8889-7

  • Online ISBN: 978-94-009-8887-3

  • eBook Packages: Springer Book Archive

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