Analysis of the Benefit of Palliation of Brain Metastases
The presentation of brain metastasis may occur in a variety of circumstances: a manifestation of progressively disseminated disease with headache or neurologic dysfunction; the concomitant presentation of brain metastasis and a primary lesion (often lung cancer); as a first sign of dissemination after a period of time with no evidence of disease. Regardless of these or other circumstances, the patient most often realizes the prognostic significance of such a finding. Analysis of the benefit of possible palliative treatment requires consideration of all of the issues. The patient, family, and physician have a direct role in decision making and each requires review. In addition, in a larger sense society plays an indirect role in the services and modalities available for patients both with potential cerebral metastasis as well as with active disease.
KeywordsGlycerol Leukemia Corticosteroid Fractionation Dexamethasone
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