Abstract
In 1962 Folse and Braunwald reported on determination of left ventricular (LV) ejection fraction, applying radionuclide indicator dilution (1). Since then, numerous investigators have evaluated central circulatory dynamics by means of radioisotope angiocardiography, either during the first passage of a radioactive bolus through the heart (2, 3, 4, 5, 6, 7, 8, 9), or after equilibrium of a tracer that remains within the circulation, using the gated cardiac blood pool technique (10,11). Applying high time resolution, the first passage of a radioactive tracer allows estimation of ventricular performance by means of (a) time parameters, especially minimal cardiac transit times (MTT) reflecting the ratio of cardiac segmental volumes to cardiac output (2, 3, 6, 7, 8, 9) and (b) by means of the ratio of end-systolic and enddiastolic activities, according to the corresponding volume ratios (4,5). This study was undertaken to test the validity of radiocardiographic parameters of ventricular performance, such as MTT as well as right and left ventricular ejection fraction (RVEF and LVEF), simultaneously measured by first-pass radionuclide angiography. Furthermore, the sensitivity and specifity of these noninvasive parameters with regard to identification of compromised RV and LV performance were determined in patients with coronary artery disease (CAD).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Folse R, Braunwald E: Determination of fraction of left ventricular volume ejected per beat and of ventricular end-diastolic and residual volumes. Circulation 25:674–685, 1962.
Schicha H, Vyska K, Becker V, Seipel L, Feinendegen LE: Minimale kardiale Transitzeiten (MTT’s) in der Herzdiagnostik, Messungen mit der Gamma-Retina und Indium-113m II: MTT’s bei verschiedenen Herzklappenfehlern. Z Kreislaufforsch 60:947–957, 1971.
Vyska K, Schicha H, Becker V, Seipel L, Feinendegen LE: Minimale kardiale Transitzeiten (MTT’s) in der Herzdiagnostik, Messungen mit der Gamma-Retina V und Indium-113m: MTT’s bei Myokardschadigung und nach Digitalisierung. Z Kreislaufforsch 61:820–827, 1972.
Van Dyke D, Anger HO, Sullivan RW, Vetter WR, Yano Y, Parker HG: Cardiac evaluation from radioisotope dynamics. J Nucl Med 13:585–592, 1972.
Schelbert HR, Verba JW, Johnson AD, Brock GW, Alazraki NP, Rose FJ, Ashburn WL: Nontraumatic determination of left ventricular ejection fraction by radionuclide angiocardiography. Circulation 51:902–909, 1975.
Tillmanns H, Knapp WH, Mehmel HC, Kübler W, Doll J, Schömig A: Regionale Myokardperfusion und Myokardfunktion: Ergebnisse eines neuen nuklearmedizinischen Verfahrens. Verh Dtsch Ges Inn Med 82:1141–1145, 1976.
Tillmanns H, Knapp WH, Mehmel HC, Kübler W, Doll J, Olshausen K von, Schömig A: Regionale Myokardperfusion und Myokardfunktion bei Myokardinfarkt mit normalem Koronar-Angiogramm. Verh Dtsch Ges Inn Med 83:249–252, 1977.
Knapp WH, Doll J: Eine automatisierte Methode zur Bestimmung von Kreislaufzeiten in der nuklearmedizinischen Herzdiagnostik. Nucl Med (in press).
Knapp WH, Tillmanns H, Doll J, Mäurer K, Georgi P: Radiokardiographie während der ersten kardialen Indikatorpassage: Vergleich zweier Prinzipien im Hinblick auf ihre Bedeutung für die quantitative Erfassung der Myokardfunktion. (In press).
Mason DT, Ashburn WL, Harbert JC, Cohen LS, Braunwald E: Rapid sequential visualization of the heart and great vessels in man using the wide-field Anger scintillation camera. Circulation 39:19–28, 1969.
Strauss HW, Zaret BL, Hurley PJ, Natarajan TK, Pitt B: A scintiphotographic method for measuring left ventricular ejection fraction in man without cardiac catheterization. Am J Cardiol 28:575–580, 1971.
Baird-Atomic: System seventy-seven, user handbook 1, vol 2.
Greene DG, Carlisle R, Grant C, Bunnell IL: Estimation of left ventricular volume by one-plane cineangiography. Circulation 35:61–69, 1967.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1980 Martinus Nijhoff Publishers bv, The Hague, Boston, London
About this chapter
Cite this chapter
Tillmanns, H., Knapp, W.H., Von Olshausen, K., Mehmel, H.C., Doll, J., Kübler, W. (1980). Validity of Parameters of Ventricular Performance Determined by Radiocardiography in Patients with Coronary Artery Disease. In: Baan, J., Arntzenius, A.C., Yellin, E.L. (eds) Cardiac Dynamics. Developments in Cardiovascular Medicine, vol 2. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8796-8_37
Download citation
DOI: https://doi.org/10.1007/978-94-009-8796-8_37
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-8798-2
Online ISBN: 978-94-009-8796-8
eBook Packages: Springer Book Archive