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The Locomotor Behaviour of Human Blood Monocytes in Chemotactic and Chemokinetic Environments and the Role of Substratum in Monocyte Locomotion

  • P. C. Wilkinson
  • R. B. Allan
  • A. Blussé van Oud Alblas

Abstract

Mononuclear phagocytes from a variety of sources, for example, blood monocytes, macrophages from peritoneal exudates or from the unstimulated peritoneal cavity, and alveolar macrophages, all show locomotor reactions to chemoattractants. In this paper we deal chiefly with blood monocytes. Although the role of macrophage chemotaxis in the evolution of inflammatory lesions is uncertain, it does at least seem probable that the monocytes which leave the blood are in the first instance directed into such lesions by chemotactic stimuli.

Keywords

Mononuclear Phagocyte Chemotactic Factor Positive Gradient Monocyte Chemotaxis Filter Assay 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media Dordrecht 1980

Authors and Affiliations

  • P. C. Wilkinson
  • R. B. Allan
  • A. Blussé van Oud Alblas

There are no affiliations available

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