Immunological reaction of psychotic patients to fractions of gluten
Production of leucocyte migration inhibition factor (LIF) by peripheral blood lymphocytes in response to challenge with gluten fractions was studied in hospitalized schizophrenics and psychotics as compared with normal individuals and children and adolescents with biopsy proven coeliac disease. The schizophrenic and psychotic patients were found to be sub-divided into two groups, one responding in the LIF test like coeliac patients and the other like the normal controls. The psychotic and schizophrenic patients did not show any evidence of malabsorption. It is speculated that in certain psychotic individuals, gluten may be involved in biological processes in the brain.
KeywordsMigration Depression Agarose Schizophrenia Polypeptide
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