Abstract
Existing algorithms for locating chromosome centromeres in digital images are insufficiently reliable for totally automatic analysis systems. However, the problem of unreliability can to some extent be overcome by the use of confidence measures at each processing stage. It is therefore desirable to combine different available algorithms in such a way as to improve both the reliability and the confidence in the location of the centromere. A combination of two methods is described, in which chords analysis acts as a “plan” for the analysis of an integrated density profile along the medial axis of the chromosome.
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© 1981 D. Reidel Publishing Company
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Piper, J. (1981). Finding Chromosome Centromeres Using Boundary and Density Information. In: Simon, J.C., Haralick, R.M. (eds) Digital Image Processing. NATO Advanced Study Institutes Series, vol 77. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8543-8_26
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DOI: https://doi.org/10.1007/978-94-009-8543-8_26
Publisher Name: Springer, Dordrecht
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