Origin of Life pp 487-493 | Cite as

Search for Primitive Replicative Properties on Early Polypeptides

  • André Brack
  • Gérard Spach
Conference paper


The sequences of polypeptide chains which are built up with alternating hydrophilic-hydrophobic residues concentrate them-selves in the β-pleated sheet conformation when dissolved in salted water. The sheets are more stable than the α-helix and are shown to constitute a pathway to the enrichment in one enantiomer. They are considered as a single system with potential template activity.


Sugar Clay Hydrolysis Proline Polypeptide 


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Copyright information

© D. Reidel Publishing Company 1981

Authors and Affiliations

  • André Brack
    • 1
  • Gérard Spach
    • 1
  1. 1.Centre de Biophysique Moléculaire, CNRSOrléansFrance

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