Abstract
The ideal radiopharmaceutical for hepatobiliary investigations should be rapidly extracted from the blood by the hepatocytes following intravenous injection, pass rapidly through the hepatocytes and concentrate in the bile. There should be little or no reabsorption from the intestinal tract and minimal excretion in the urine. The labeling yield (with Tc99m) should be high and the product should be formulated as a sterile, pyrogen free one step labeling kit (1). The N-substituted iminodiacetic acid derivatives suggested by Loberg in 1976 (2) fulfil many of these requirements.
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© 1981 Martinus Nijhoff Publishers, The Hague
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Cox, P.H. (1981). The Chemistry and Pharmacy of Ida-Derivatives. In: Cox, P.H. (eds) Cholescintigraphy. Developments in Nuclear Medicine, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8325-0_3
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DOI: https://doi.org/10.1007/978-94-009-8325-0_3
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