Abstract
The immunopathologic features of systemic lupus erythematosus appear analogous to the vascular lesions found in experimental serum sickness (1). Ultrastructural and immunopathologic studies reveal the deposition of immune aggregates not only in various renal structures, but also in the pulmonary alveolar capillary bed (2), myocardial vessels (3), choroid plexus (4) and the media of larger arteries (5). Because the development vascular lesions in experimental acute serum sickness appears at a time when there are circulating immune complexes, much attention has been centered around the role of these complexes in the pathogenesis of inflammatory diseases of small vessels.
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References
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© 1981 Martinus Nijhoff Publishers, The Hague
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Lewis, E.J., Roberts, J.L. (1981). Circulating Immune Complexes and Systemic Lupus Erythematosus. In: Gruskin, A.B., Norman, M.E. (eds) Pediatric Nephrology. Developments in Nephrology, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8319-9_44
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DOI: https://doi.org/10.1007/978-94-009-8319-9_44
Publisher Name: Springer, Dordrecht
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