The Kidney Following Cardiac Surgery

  • T. M. Barratt
  • S. P. A. Rigden
Part of the Developments in Nephrology book series (DINE, volume 3)


The kidneys receive one quarter of the cardiac output: it is therefore hardly surprising that impairment of renal function is a major complication of cardiopulmonary by-pass surgery (CPBS) with a high mortality, both in adults and children (1). The principal cause is undoubtedly renal hypoperfusion resulting from a low cardiac output, but other factors may be additive: before surgery there is to consider the physiological characteristics of the neonatal kidney and the questions of congenital renal abnormality, cyanotic nephropathy and the nephrotoxicity of radiological contrast media; during CPBS there is the possible effect of haemolysis; and subsequently there may be septicaemia or drug nephrotoxicity (particularly antibiotics).


Peritoneal Dialysis Urine Flow Rate Plasma Creatinine Concentration Arrest Time Cortical Perfusion 
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  1. 1.
    Rigden SPA, Barratt TM, Dillon MJ, de Leval M, Stark J. 1980. Acute renal failure complicating cardiopulmonary bypass surgery in children. Submitted for publication.Google Scholar
  2. 2.
    Spitzer A. 1978. Renal physiology and functional development. In: Edelmann CM (ed.) Pediatric Kidney Disease, pp. 25–127. Boston, Little, Brown and Company.Google Scholar
  3. 3.
    Rigden SPA. 1980. Renal function after cardiopulmonary bypass surgery. In preparation.Google Scholar

Copyright information

© Martinus Nijhoff Publishers, The Hague 1981

Authors and Affiliations

  • T. M. Barratt
  • S. P. A. Rigden

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