Abstract
The kidneys receive one quarter of the cardiac output: it is therefore hardly surprising that impairment of renal function is a major complication of cardiopulmonary by-pass surgery (CPBS) with a high mortality, both in adults and children (1). The principal cause is undoubtedly renal hypoperfusion resulting from a low cardiac output, but other factors may be additive: before surgery there is to consider the physiological characteristics of the neonatal kidney and the questions of congenital renal abnormality, cyanotic nephropathy and the nephrotoxicity of radiological contrast media; during CPBS there is the possible effect of haemolysis; and subsequently there may be septicaemia or drug nephrotoxicity (particularly antibiotics).
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References
Rigden SPA, Barratt TM, Dillon MJ, de Leval M, Stark J. 1980. Acute renal failure complicating cardiopulmonary bypass surgery in children. Submitted for publication.
Spitzer A. 1978. Renal physiology and functional development. In: Edelmann CM (ed.) Pediatric Kidney Disease, pp. 25–127. Boston, Little, Brown and Company.
Rigden SPA. 1980. Renal function after cardiopulmonary bypass surgery. In preparation.
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© 1981 Martinus Nijhoff Publishers, The Hague
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Barratt, T.M., Rigden, S.P.A. (1981). The Kidney Following Cardiac Surgery. In: Gruskin, A.B., Norman, M.E. (eds) Pediatric Nephrology. Developments in Nephrology, vol 3. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8319-9_35
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DOI: https://doi.org/10.1007/978-94-009-8319-9_35
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-009-8321-2
Online ISBN: 978-94-009-8319-9
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