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Epidemiological Evidence for a Hereditary Component in Crohn’s Disease

  • B. I. Korelitz
Part of the Developments in Gastroenterology book series (DIGA, volume 1)

Abstract

Evidence for a significant familial incidence of Crohn’s disease has been presented from many sources (1–5). Despite this, geneticists have not yet concluded that this familial association has a hereditary basis. The traditional lines of investigation of the past into the etiology of Crohn’s disease such as dietary and psychosomatic have lost their enthusiasts, immunological factors seem to have a supplementary role and even the recently promising microbiological transmission studies warrant less hope than earlier (6). It is therefore understandable for the gastroenterologist to turn once again to his patients to find whether the strong familial association observed clinically is statistically significant and whether any new direction for further investigation might be forthcoming through this route.

Keywords

Inflammatory Bowel Disease Ulcerative Colitis Familial Association Hereditary Component Flammatory Bowel Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishers bv, The Hague 1981

Authors and Affiliations

  • B. I. Korelitz

There are no affiliations available

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