General Discussion and Conclusions

  • T. Gilat
Part of the Developments in Gastroenterology book series (DIGA, volume 1)


Available epidemiologic evidence and data presented here strongly implicate environmental factors in the causation of CD. The evidence may be summarized as follows:
  1. 1.

    There is a rising incidence of the disease in recent decades in developed as well as developing countries. This rise seems to be too rapid to explain by genetic changes.

  2. 2.

    Changes in the incidence of the disease have occurred in migrant populations such as Ashkenazi Jews.

  3. 3.

    The incidence of the disease in populations of developing countries has risen with urbanization and industrialization or with migration to such areas.



Public Health Environmental Factor Genetic Factor Incubation Period Recent Decade 
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Copyright information

© Martinus Nijhoff Publishers bv, The Hague 1981

Authors and Affiliations

  • T. Gilat

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