Skip to main content

The Epidemiology of Crohn’s Disease, Trends and Clues

  • Chapter
Recent Advances in Crohn’s Disease

Part of the book series: Developments in Gastroenterology ((DIGA,volume 1))

  • 16 Accesses

Abstract

Epidemiologic studies performed by numerous investigators, many of them present here, have produced data which may be of help in elucidating the etiology of Crohn’s disease. In recent decades medical research was focussed on possible endogenous causes; now the pendulum has swung again and the search is on for possible exogenous causes. I would like to submit that available epidemiological information supports the predominance of exogenous or environmental factors in the causation of Crohn’s disease. This evidence may be grouped under 3 headings: a] Rapidly increasing incidence of the disease in defined populations, b] study of a migrant populations Ashkenazi Jews and c] the very low [and rising] incidence in several developing populations.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Mayberry J, Rhodes J, Hughes LE. (1979) Epidemiology. Incidence of Crohn’s disease in Cardiff between 1934 and 1977. Gut 20:602–608

    Article  PubMed  CAS  Google Scholar 

  2. Kyle J. (1971) An epidemiological study of Crohn’s disease in northeast Scotland. Gastroenterology 61:826–833

    PubMed  CAS  Google Scholar 

  3. Miller DS, Keighley AC, Langman MJS. (1974) Changing patterns in epidemiology of Crohn’s disease. Lancet 2:691–693

    Article  PubMed  CAS  Google Scholar 

  4. Bergman L, Krause U. (1975) The incidence of Crohn’s disease in central Sweden. Scand.J.Gastroenterol. 10:725–729

    PubMed  CAS  Google Scholar 

  5. Kewenter J, Hulten L, Kock NG. (1974) The relationship and epidemiology of acute terminal ileitis and Crohn’s disease. Gut 15:801–804

    Article  PubMed  CAS  Google Scholar 

  6. Brahme F, Lindstrom C, Wenckert A. (1975) Crohn’s disease in a defined population. An epidemiological study of incidence, prevalence, mortality, and secular trends in the city of Malmo, Sweden. Gastroenterology 69:342–351

    PubMed  CAS  Google Scholar 

  7. Hoj L, Jensen PB, Bonnevie O, Riis P. (1973) An epidemiological study of regional enteritis and acute ileitis in Copenhagen County. Scand.J.Gastroenterol. 8:381–384

    PubMed  CAS  Google Scholar 

  8. Fahrlander H, Baerlocher C. (1971) Clinical features and epidemiological data on Crohn’s disease in the Basle area. Scand.J.Gastroenterol. 6:657–662

    Article  PubMed  CAS  Google Scholar 

  9. Rozen P, Zonis J, Yekutiel P, Gilat T. (1979) Crohn’s disease in the Jewish population of Tel-Aviv-Yafo. Gastroenterology 76:25–30

    PubMed  CAS  Google Scholar 

  10. Novis BH, Marks IN, Bank S, Louw JH. (1975) Incidence of Crohn’s Disease at Groote Schuur Hospital during 1970–1974. S.Afr.Med.J. 49:693–697

    PubMed  CAS  Google Scholar 

  11. Monk M, Mendeloff AI, Siegel CI, Lilienfeld A. (1967) An epidemiological study of ulcerative colitis and regional enteritis among adults in Baltimore. I. Hospital incidence and prevalence, 1960 to 1963. Gastroenterology 53:198–210

    Google Scholar 

  12. Acheson ED. (1960) The distribution of ulcerative colitis and regional enteritis in United States veterans with particular reference to the Jewish religion. Gut 1:291–293

    Article  PubMed  CAS  Google Scholar 

  13. Weiner HA, Lewis CM. (1960) Some notes on the epidemiology of nonspecific ulcerative colitis. An apparent increase in incidence in Jews. Am.J.Dig.Dis. 5:406–418

    Article  PubMed  CAS  Google Scholar 

  14. Nefzger MD, Acheson ED. (1963) Ulcerative colitis in the United States Army in 1944. Follow-up with particular reference to mortality in cases and controls. Gut 4:183–192

    Article  PubMed  CAS  Google Scholar 

  15. Rogers BHG, Clark LM, Kirsner JB. (1971) The epidemiologic and demographic characteristics of inflammatory bowel disease: an analysis of a computerized file of 1,400 patients. J.Chron.Dis. 24:743–773

    Article  PubMed  CAS  Google Scholar 

  16. Gilat T. (1979) Lactase Deficiency: The world pattern today. Isr. J.Med.Sci. 15:369

    PubMed  CAS  Google Scholar 

  17. Tandon R, Mandell H, Spiro HM, Thayer WR.Jr. (1971) Lactose intolerance in Jewish patients with ulcerative colitis. Am.J.Dig.Dis. 16:845–848

    Article  PubMed  CAS  Google Scholar 

  18. Leichter J. (1971) Lactose tolerance in a Jewish population. Am.J.Dig.Dis. 16:1123–1126

    Article  Google Scholar 

  19. Walker ARP, Segal I. (1979) Epidemiology of non-infective intestinal diseases in various ethnic groups in South Africa. Isr.J.Med.Sci. 15:309–313

    PubMed  CAS  Google Scholar 

  20. Hutt MSR. (1979) Epidemiology of chronic intestinal disease in middle Africa. Isr.J.Med.Sci. 15:314–317

    PubMed  CAS  Google Scholar 

  21. Lee SK. (1974) Crohn’s disease in Singapore. Med.J.Aust. 1:266–269

    PubMed  CAS  Google Scholar 

  22. Das SK, Montgomery RD. (1978) Chronic inflammatory bowel disease in Asian immigrants. Practitioner 221:747–749

    PubMed  CAS  Google Scholar 

  23. Myren J, Bouchier IAD, Watkinson G, deDombal FT. (1979) Inflammatory bowel disease an OMGE survey. Scand.J.Gastroenterol. 14 (Suppl.)56:1–29

    CAS  Google Scholar 

  24. Gilat T, Rozen P. (1979) Epidemiology of Crohn’s disease and ulcerative colitis: etiologic implications. Isr.J. Med.Sci. 15:305–308

    PubMed  CAS  Google Scholar 

  25. Gilat T. (1979) Etiology of inflammatory bowel disease. J.Clin.Gastroenterol. 1:299

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1981 Martinus Nijhoff Publishers bv, The Hague

About this chapter

Cite this chapter

Gilat, T., Rozen, P. (1981). The Epidemiology of Crohn’s Disease, Trends and Clues. In: Peña, A.S., Weterman, I.T., Booth, C.C., Strober, W. (eds) Recent Advances in Crohn’s Disease. Developments in Gastroenterology, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-8273-4_33

Download citation

  • DOI: https://doi.org/10.1007/978-94-009-8273-4_33

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-009-8275-8

  • Online ISBN: 978-94-009-8273-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics